Fas Signaling

Herausgegeben:Wajant, Harald

• Broschiertes Buch

Produktbeschreibung

Fas Signaling is focused on the signaling mechanisms and biology of the prototypic death receptor Fas, also called CD95 or APO-1. The chapters of this book cover, besides the well recognized apoptosis-related functions of Fas, its emerging role as a proinflammatory cytokine and as an inducer of alternative forms of cell death. Fas Signaling aims to provide the reader with an up-to-date survey of the various aspects of Fas biology and the open questions of the field are addressed. This title is intended for Ph.D and post-doctoral students starting to work in the field, but is also useful for everyone with an interest in the biology of this exciting molecule.

Produktdetails

• Medical Intelligence Unit
• Verlag: Landes Bioscience / Springer / Springer US / Springer, Berlin
• Artikelnr. des Verlages: 978-1-4419-4074-2
• Softcover reprint of hardcover 1st ed. 2006
• Seitenzahl: 172
• Erscheinungstermin: 23. November 2010
• Englisch
• Abmessung: 248mm x 165mm x 10mm
• Gewicht: 259g
• ISBN-13: 9781441940742
• ISBN-10: 144194074X
• Artikelnr.: 32135605

Inhaltsangabe

FasL and Fas.- FasL-Independent Activation of Fas.- Role of Ceramide in CD95 Signaling.- Regulation of Fas Signaling by FLIP Proteins.- Fas-Induced Necrosis.- Fas-More Than an Apoptosis Inducer.- Retrograde Fas Ligand Signaling.- FasL and Fas in Liver Homeostasis and Hepatic Injuries.- Fas-Activation, Development and Homeostasis of T Cells.- The FasL-Fas System in Disease and Therapy.- Tools for Activation and Neutralization of Fas Signaling.