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The Arabian horse is commonly believed to be one of the oldest horse breeds and the only purebred in the equine world. It is the most valuable, expensive species of equine as it combines unique and different characteristics than other breeds and other species of animals, which qualify it to be the breed of choice for long distance trail competitions and international festivals, hence has a great role in the improvement of the country's economy. This study aimed to establish a reliable DNA test for detection of asymptomatic SCID carriers in the Egyptian Arabian horse population and to re-examine cases of unexplained foal death to exclude presence of SCID disease. Live samples were chosen at random from the registered population as well as post-mortem samples from reported cases died at different ages in Arabians farms. No SCID cases were found among the examined groups.