Film cooling is the mechanism which supplies bleed compressor air from internal convective passages onto the surface of an airfoil in order to protect the surface from excessive heat loads. The resulting flowfield is extremely complex, and the efficiency of a cooling scheme is very sensitive to the details of the geometrical and physical conditions. This book provides a comprehensive computational study of film cooling from inclined cylindrical holes issued into a turbulent boundary layer with a high-fidelity turbulence modeling approach - Large Eddy Simulations. It starts with the details of the numerical methodology developed for the simulations, including its testing and validation. It proceeds with the documentation of the results of the cooling simulations, presents an extensive analysis of the flow physics, thermal properties and cooling efficiency, as well as the detailed comparison with experiments. Engineers and scientists interested in developing computational software for simulating turbulent flows, as well as professionals in gas turbine industry, and anyone interested in heat transfer and fluid dynamics, will find this book a valuable reference.