The book gives a unique overview of this rapidly developing research field, presenting structures and properties of flavin derivatives as well as their proven application as bioinspired catalysts in various organocatalytic, biocatalytic, and photocatalytic reactions.
The book gives a unique overview of this rapidly developing research field, presenting structures and properties of flavin derivatives as well as their proven application as bioinspired catalysts in various organocatalytic, biocatalytic, and photocatalytic reactions.
Radek Cibulka is Full Professor and Head of the Department of Organic Chemistry at the University of Chemistry and Technology (UCT) in Prague, Czech Republic. He has authored over 60 scientific publications and received numerous scientific awards, including "Alfred Bader Prize", which is given by the Czech Chemical Society and the Alfred Bader Foundation to young scientists under 35 years. His research interests lie in chemistry and photochemistry of flavins and their application in organo- and photocatalysis. Marco Fraaije is Full Professor and heading the Molecular Enzymology group at the University of Groningen (RUG) in Groningen, The Netherlands. He has authored over 200 scientific publications and received numerous scientific awards, including the BIOCAT-science award (2018). His research focuses on the discovery, engineering and exploration of redox enzymes, with special emphasis on flavin-containing enzymes. Besides exploring the biocatalytic potential of these biocatalysts, he also aims at elucidating the molecular functioning of (flavo)enzymes.
Inhaltsangabe
Structure and properties of flavins Natural flavins: occurrence, role and non-canonical chemistry Spectral properties of flavins Modes of flavin-based catalysis Organocatalytic monooxygenations Flavin-based supramolecular and coupled catalytic systems Flavoprotein monooxygenases and halogenases Flavoprotein-dependent bioreduction Flavoprotein oxidases Benzylic photooxidation by flavins New applications of flavin photocatalysis Light-driven flavin-based biocatalysis
Structure and properties of flavins Natural flavins: occurrence, role and non-canonical chemistry Spectral properties of flavins Modes of flavin-based catalysis Organocatalytic monooxygenations Flavin-based supramolecular and coupled catalytic systems Flavoprotein monooxygenases and halogenases Flavoprotein-dependent bioreduction Flavoprotein oxidases Benzylic photooxidation by flavins New applications of flavin photocatalysis Light-driven flavin-based biocatalysis
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