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The seriousness and societal costs of dental caries are enormous. The current oral health care trend is improvising on evidence-based recommendations and treatment. The current use of fluoride varnish in the prevention of dental caries is based on community, professional, and individual strategies. These regimens should include a risk analysis and a review of the patient's current fluoride exposure. A search of the literature on fluoride varnish was carried out in electronic databases, reference lists of articles, and selected textbooks. This book highlights the caries-preventive effect of professional fluoride varnish treatments. Its effectiveness; application ease and safety give them an advantage over other types of topical fluoride treatments. This book is excellent for Dental students, for research scholars and for dental practitioners who practice preventive dentistry.