The world economy has considerable experience in the formation and functioning of innovation clusters at the regional level, which should be taken into account in the cluster policy of the Republic of Uzbekistan. This book summarizes foreign experience, which for the economic environment of local economic policy is very important in the period of formation on market relations. Formation of regional territorial clusters and stimulation of their growth is one of the most important among the socio-economic challenges faced by modern Uzbekistan. Without solving them, it is impossible to make the transition from the raw material model of development to the knowledge economy, the growth points of which are clusters.