Formazans as Chemotherapeutic Agents - Ankem, Narendra Babu;Nadendla, Rama Rao
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Medicinal Chemistry and drug development reached the conclusion that natural substances and synthetic compounds are complementary as sources for new drugs.The natural compound needs to be modified synthetically to enhance its desirable medicinal properties, or to reduce its toxic properties. In present study potentially therapeutic carboxyphenyl formazans, pyrimidine formazans and quinazolinone formazans were synthesized and were characterized.All synthesized compounds were subjected for in-vitro antibacterial, in-vitro antifungal, in-vitro analgesic, in-vitro anti-inflammatory and in-vitro…mehr

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Produktbeschreibung
Medicinal Chemistry and drug development reached the conclusion that natural substances and synthetic compounds are complementary as sources for new drugs.The natural compound needs to be modified synthetically to enhance its desirable medicinal properties, or to reduce its toxic properties. In present study potentially therapeutic carboxyphenyl formazans, pyrimidine formazans and quinazolinone formazans were synthesized and were characterized.All synthesized compounds were subjected for in-vitro antibacterial, in-vitro antifungal, in-vitro analgesic, in-vitro anti-inflammatory and in-vitro anthelmintic activities. This work provides excellent approach for the synthesis of pharmacologically active and important formazans derivatives.
Autorenporträt
Dr. Narendra Babu Ankem is a professor at Chalapathi Institute of Pharmaceutical Sciences, Guntur where he serving as Head of the Department, Dept. of Pharmacology.He has 15 years of teaching and research experience. Expert in Clinical as well Preclinical studies. He is the author of many scientific publications.