Formulation and Characterization of Aceclofenac Microsphere - Verma, Sofiya;Chaurasia, Sandhya;Asati, Ashok
32,99 €
inkl. MwSt.
Versandkostenfrei*
Versandfertig in 6-10 Tagen
  • Broschiertes Buch

The purpose of this research was to prepare and characterize Aceclofenac microsphere of guar gum polymer for the application of inflammation. Method: - The microsphere were prepared by using emulsification method using starch cross-linked agent and coating was done by solvent evaporation method with the pH sensitive eudragit S-100 polymers. Result:-The prepared microsphere were white, free flowing and spherical in shape. The drug-loaded microsphere showed entrapment efficiency and drug release was extended upto 6 to 8 h. The infrared spectra, differential scanning calorimetry thermographs…mehr

Andere Kunden interessierten sich auch für
Produktbeschreibung
The purpose of this research was to prepare and characterize Aceclofenac microsphere of guar gum polymer for the application of inflammation. Method: - The microsphere were prepared by using emulsification method using starch cross-linked agent and coating was done by solvent evaporation method with the pH sensitive eudragit S-100 polymers. Result:-The prepared microsphere were white, free flowing and spherical in shape. The drug-loaded microsphere showed entrapment efficiency and drug release was extended upto 6 to 8 h. The infrared spectra, differential scanning calorimetry thermographs spectra all showed the stable character of both the drugs in the drug-loaded microspheres and revealed the absence of drug-polymer interactions. Scanning electron microscopy study revealed that the microspheres were spherical and porous in nature. The stability study was conducted to conform the stability of prepared microsphere. In-vitro drug release study was performed in both simulated gastrointestinal fluid medium and rat cecal content of different pH. Conclusion:-The prepared Aceclofenac microsphere has the potential for delaying the release of drug.
Autorenporträt
Sofiya Verma completed her M Pharmacy fromRajiv Gandhi Technical University Bhopal M.P.(India)Sofiya Verma having excellent academicsrecord. She is currently working as Asst. Professor at daksh institute of pharmaceutical science chhatarpur (M.P)