Formulation and Evaluation of Hydrogel of Antihypertensive Drug - Mohite, Popat;Adhav, Sonali
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In this Book, Losartan Potassium Hydrogel was prepared by co-polymerization method using Potassium persulfate as a catalyst , Ascorbic Acid as a catalyst , Distilled Water as a vehicle , N-N Methylene bis acrylamide as cross linker , Acrylic Acid as a homopolymer , Acrylamide as a homopolymer drug solution contain Losartan Potassium as a antihypertensive The HPLC study was performed for Losartan Potassium in Triethylamine: Acetonitrile (60:40 v/v) which exhibited retention time 5.23 min. The appearance study was found to be colorless liquid solution at various days that indicates stability of…mehr

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Produktbeschreibung
In this Book, Losartan Potassium Hydrogel was prepared by co-polymerization method using Potassium persulfate as a catalyst , Ascorbic Acid as a catalyst , Distilled Water as a vehicle , N-N Methylene bis acrylamide as cross linker , Acrylic Acid as a homopolymer , Acrylamide as a homopolymer drug solution contain Losartan Potassium as a antihypertensive The HPLC study was performed for Losartan Potassium in Triethylamine: Acetonitrile (60:40 v/v) which exhibited retention time 5.23 min. The appearance study was found to be colorless liquid solution at various days that indicates stability of solution. The density, viscosity, pH, drug content were found to be in the standard ranges only. It will be guide for researcher in Hydrogel formulation.
Autorenporträt
Dr. P.B. Mohite, Professor Associado e Diretor do Departamento de Química Farmacêutica e Estudos de PG na Faculdade de Farmácia da MES, Sonai. Publicou 75 trabalhos de investigação em várias revistas de renome nacional e internacional. É revisor e membro do conselho editorial de várias revistas. Orientou 16 estudantes de pós-graduação.