Formulation and Optimization of Colon Targeted Microcapsules - Solanki, Dharmendra;Raghuvanshi, Rupali
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In present work attempts have been made to formulate and evaluate colontargeted capsules of Ibuprofen by using polymer Sodium alginate, Xanthangum, Chitosen and Eudragit used as coating. Ibuprofen show anti-inflammatory activity. Ibuprofen meets all the ideal characteristics to formulate in the form of colon drug delivery system. Mucoadhesive polymers whose mucoadhesive properties had been reported were used along with alginate for the preparation of capsules. The mucoadhesive polymers used in the formulations were xanthan gum, eudragit, and chitosan. The capsules were prepared by orifice ionic gelation method.…mehr

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Produktbeschreibung
In present work attempts have been made to formulate and evaluate colontargeted capsules of Ibuprofen by using polymer Sodium alginate, Xanthangum, Chitosen and Eudragit used as coating. Ibuprofen show anti-inflammatory activity. Ibuprofen meets all the ideal characteristics to formulate in the form of colon drug delivery system. Mucoadhesive polymers whose mucoadhesive properties had been reported were used along with alginate for the preparation of capsules. The mucoadhesive polymers used in the formulations were xanthan gum, eudragit, and chitosan. The capsules were prepared by orifice ionic gelation method.
Autorenporträt
Prof (Dr.) Dharmendra Solanki is working as Professor and Principal at LNCP Indore. He earned PhD degree in pharmacy from Department of pharmaceutical science Berhampur University, Orrisa; and worked on Formulation, Design and Development of Novel Sustained Release Solid Dosage Form of Selected Drug.