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Inflammatory response to bacterial biofilm at or below the gingival margin results in plaque-induced gingivitis. In other words, an inflammatory infiltrate consisting of, but not limited to, polymorphonuclear leukocytes, lymphocytes, erythrocytes and histiocytes accumulates in the underlying lamina propria. Page and Schroeder presented the classic gingival morpho-histopathologic features in response to this plaque biofilm etiology.