This issue of Progress in Brain Research is split over 2 volumes, bringing together cutting-edge research on functional neural transplantation. The 2 volumes review current knowledge and understanding, provide a starting point for researchers and practitioners entering the field, and build a platform for further research and discovery.
This issue of Progress in Brain Research is split over 2 volumes, bringing together cutting-edge research on functional neural transplantation. The 2 volumes review current knowledge and understanding, provide a starting point for researchers and practitioners entering the field, and build a platform for further research and discovery.
1. Preface Stephen Dunnett and Anders Björklund 2. Transplantation in the Future Fred H. Gage 3. Ethical Challenges for Using Human Cells in Clinical Cell Therapy Göran Hermerén 4. Banking Stem Cells for Research and Clinical Applications Glyn Stacey 5. Survival, Differentiation and Connectivity of Ventral Mesencephalic Dopamine Neurons following Transplantation Lachlan Thompson and Anders Björklund 6. Electrophysiological Investigations of Synaptic Connectivity between Host and Graft Neurons Jan Tønnesen and Merab Kokaia 7. Nigral Grafts in Animal Models of Parkinson's Disease. Is Recovery beyond Motor Function Possible? Mariah J. Lelos, Eilís Dowd and Stephen B. Dunnett 8. L-DOPA- and Graft-Induced Dyskinesia following Transplantation Emma L. Lane and Christian Winkler 9. Current Status of Clinical Trials of Neural Transplantation in Parkinson's Disease Jonathan R Evans, Sarah L Mason and Roger A Barker 10. In vivo Imaging of the Integration and Function of Nigral Grafts in Clinical Trials Marios Politis and Paola Piccini 11. Neuropathology in Transplants in Parkinson's Disease: Implications for Disease Pathogenesis and the Future of Cell Therapy Patrik Brundin and Jeffrey H. Kordower 12. Derivation of Dopaminergic Neurons from Pluripotent Stem Cells Lorenz Studer 13. Characterization and Criteria of Embryonic Stem and Induced Pluripotent Stem Cells for a Dopamine Replacement Therapy Oliver Cooper, Malin Parmar and Ole Isacson 14. Skilled Motor Control for the Preclinical Assessment of Functional Deficits and Recovery following Nigral and Striatal Cell Transplantation Alexander Klein and Ian Q. Whishaw 15. Role of Experience, Training and Plasticity in the Functional Efficacy of Striatal Transplants Máté D. Döbrössy and Guido Nikkhah 16. In vivo Imaging of Integration and Function of Striatal Grafts in Rodent and Non-Human Primate Animal Models Philippe Hantraye and Romina Aron Badin 17. Clinical Trials of Neural Transplantation in Huntington's Disease Anne E. Rosser and Anne-Catherine Bachoud-Lévi 18. Derivation of Striatal Neurons from Human Stem Cells Pedro Viegas, Camille Nicoleau and Anselme L. Perrier
1. Preface Stephen Dunnett and Anders Björklund 2. Transplantation in the Future Fred H. Gage 3. Ethical Challenges for Using Human Cells in Clinical Cell Therapy Göran Hermerén 4. Banking Stem Cells for Research and Clinical Applications Glyn Stacey 5. Survival, Differentiation and Connectivity of Ventral Mesencephalic Dopamine Neurons following Transplantation Lachlan Thompson and Anders Björklund 6. Electrophysiological Investigations of Synaptic Connectivity between Host and Graft Neurons Jan Tønnesen and Merab Kokaia 7. Nigral Grafts in Animal Models of Parkinson's Disease. Is Recovery beyond Motor Function Possible? Mariah J. Lelos, Eilís Dowd and Stephen B. Dunnett 8. L-DOPA- and Graft-Induced Dyskinesia following Transplantation Emma L. Lane and Christian Winkler 9. Current Status of Clinical Trials of Neural Transplantation in Parkinson's Disease Jonathan R Evans, Sarah L Mason and Roger A Barker 10. In vivo Imaging of the Integration and Function of Nigral Grafts in Clinical Trials Marios Politis and Paola Piccini 11. Neuropathology in Transplants in Parkinson's Disease: Implications for Disease Pathogenesis and the Future of Cell Therapy Patrik Brundin and Jeffrey H. Kordower 12. Derivation of Dopaminergic Neurons from Pluripotent Stem Cells Lorenz Studer 13. Characterization and Criteria of Embryonic Stem and Induced Pluripotent Stem Cells for a Dopamine Replacement Therapy Oliver Cooper, Malin Parmar and Ole Isacson 14. Skilled Motor Control for the Preclinical Assessment of Functional Deficits and Recovery following Nigral and Striatal Cell Transplantation Alexander Klein and Ian Q. Whishaw 15. Role of Experience, Training and Plasticity in the Functional Efficacy of Striatal Transplants Máté D. Döbrössy and Guido Nikkhah 16. In vivo Imaging of Integration and Function of Striatal Grafts in Rodent and Non-Human Primate Animal Models Philippe Hantraye and Romina Aron Badin 17. Clinical Trials of Neural Transplantation in Huntington's Disease Anne E. Rosser and Anne-Catherine Bachoud-Lévi 18. Derivation of Striatal Neurons from Human Stem Cells Pedro Viegas, Camille Nicoleau and Anselme L. Perrier
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