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Nicotine like several other drugs of abuse acts on the brain reward system. Altered function of the mesocorticolimbic system has been associated with the transition from controlled drug intake to a compulsive, uncontrolled drug consumption characterizing addicted behavior. This study was performed using functional Magnetic Resonance Imaging (fMRI) (i) to investigate changes in brain activity in the reward system in response to different stimulus categories including non-substance related motivational stimuli (erotic stimuli, beautiful faces) and substance related stimuli (smoking-related…mehr

Produktbeschreibung
Nicotine like several other drugs of abuse acts on
the brain reward system. Altered function of the
mesocorticolimbic system has been associated with the
transition from controlled drug intake to a
compulsive, uncontrolled drug consumption
characterizing addicted behavior.
This study was performed using functional Magnetic
Resonance Imaging (fMRI) (i) to investigate changes
in brain activity in the reward system in response to
different stimulus categories including
non-substance related motivational stimuli (erotic
stimuli, beautiful faces) and substance related
stimuli (smoking-related stimuli) compared to neutral
stimuli; (ii) to find out which category of
non-substance related motivational stimuli, beautiful
faces or erotic stimuli, leads to a stronger
activation in the regions of interest; and (iii) to
determine the influence of two different experimental
fMRI designs, a blocked and an event-related design,
on activation patterns in the brain reward system.
Autorenporträt
Graduated in Psychology (Dipl.-Psych.) and Neuroscience (M.Sc.)
at the University in Tübingen in 2003. After finishing her PhD at
the Graduate School of Neural & Behavioural Sciences
/International Max Planck Research School in Tübingen she worked
in the UK at the University of Cambridge and at King s
College London.