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A kinematic motor organisation which is crucial for performing different functional tasks is mediated by a distinct motor functional architecture of the central nervous system. A breakdown of this architectural network occurs in most neurological condition with motor impairment. Therefore a planned physical intervention to restore impaired structure architectural network of the brain is essential for the functional recovery. This book has dealt with four common conditions and for each condition it has identified structure of architectural network is damaged. Then the intervention strategy has elaborated the some of the precisely shaped stimulation that can restore the impaired structure, which has used wide range of research based evidences.