Gamma-Delta T Cells: Unseen Immune Warriors - Shalini
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Our bodies need protection against pathogen invasion and for that we employ our immune system which is armed with an arsenal of cells and proteins. This immune network is destined to eliminate microbes and substances determined to pose significant threat to the normal functioning of our bodies by confronting viruses, bacteria, toxins, fungi and parasites, or even by battling tumoral cells. So, the immune system develops mechanisms at least equal in effectiveness and ingenuity to the infectious or transforming threat. At the same time, the maintenance of homeostasis and prevention of…mehr

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Produktbeschreibung
Our bodies need protection against pathogen invasion and for that we employ our immune system which is armed with an arsenal of cells and proteins. This immune network is destined to eliminate microbes and substances determined to pose significant threat to the normal functioning of our bodies by confronting viruses, bacteria, toxins, fungi and parasites, or even by battling tumoral cells. So, the immune system develops mechanisms at least equal in effectiveness and ingenuity to the infectious or transforming threat. At the same time, the maintenance of homeostasis and prevention of self-destruction is a very important function managed also by the immune system via tolerance mechanisms. This orchestration and customisation of the immune system aim in securing our best survival1,2. The network of immune cells is usually divided into the innate and adaptive leg (figure I.1). The first harbours ready-for-action cells (e.g. monocytes, neutrophils, natural killer cells) and the second highly specialised agents (T and B lymphocytes). Even though separated in categories the cross talks and cooperation between the two legs are constant and crucial. T and B lymphocytes recognise and bind a broad range of antigens through the highly diverse antigen receptors on their surface (T-cell receptor for T lymphocytes and B-cell receptor for B lymphocytes) and confer the essential aspect of immunological memory1. In the T spectrum, there are unconventional cases of more rapid responders such as mucosal-associated invariant T (MAIT) cells ( beta), natural killer T (NKT) cells ( beta) or the Gammad T cells3. The focus of this work is on the human Gammad T cells and especially the VGamma9Vd2 T cell population which provide unique functional specialisation.
Autorenporträt
Professor Shalini, for your Games and Culture course, I propose "From Iron to Elite: A Gamer's Grit." This book dives deeper than the glitz of esports, exploring the dedication and mental strength required to become a top gamer. It follows a player's journey, from struggling in the "iron" ranks to the elite levels of competition. "From Iron to Elite" analyzes the key differences between casual and elite players. We'll explore how to develop a growth mindset, build mental resilience, and overcome challenges on the path to mastery. But it's not just about the game ¿ the book emphasizes a holistic approach. We'll delve into time management, healthy habits, and building a strong work ethic, all essential for peak performance. The book delves into the psychology of champions, analyzing how elite gamers manage stress, develop mental toughness, and stay focused under pressure. By understanding the mental game, aspiring gamers can unlock their full potential. "From Iron to Elite" is a valuable resource for anyone in your course interested in competitive gaming, offering them the tools and mindset to transform from casual players to elite competitors.