Gamma-hydroxybutyrate (GHB) has come a long way since early experiments in animals where it was found to induce a sleep-like state and from its use in general anaesthesia in human subjects. Gamma-Hydroxybutyrate: Pharmacological and Functional Aspects brings together the combined expertise of many of the leading authorities on the biochemistry, physiology, and pharmacology of GHB in the central nervous system. Each chapter is an in-depth review of the field and the book itself will appeal to all neurobiologists interested in neurotransmitter mechanisms, as well as to clinicians and other health-care workers interested in this fascinating chemical.…mehr
Gamma-hydroxybutyrate (GHB) has come a long way since early experiments in animals where it was found to induce a sleep-like state and from its use in general anaesthesia in human subjects. Gamma-Hydroxybutyrate: Pharmacological and Functional Aspects brings together the combined expertise of many of the leading authorities on the biochemistry, physiology, and pharmacology of GHB in the central nervous system. Each chapter is an in-depth review of the field and the book itself will appeal to all neurobiologists interested in neurotransmitter mechanisms, as well as to clinicians and other health-care workers interested in this fascinating chemical.
Metabolism and Distribution of Gamma Hydroxybutyrate in the Brain. The Gamma hydroxybutyrate Receptor in the Brain. Part of the Pharmacological Actions of Gamma hydroxybutyrate Are Mediated by GABAB Receptors. Membrane Transport of Gamma hydroxybutyrate. Action of Gamma hydroxybutyrate on Neuronal Excitability and Underlying Membrane Conductances. Regulation of Central Dopamine by Gamma hydroxybutyrate. Effects of Gamma hydroxybutyrate on Sleep. Gamma hydroxybutyrate and Absence Seizure Activity. Behavioral Pharmacology of Gamma hydroxybutyrate. Therapeutic Uses of Gamma hydroxybutyrate. Abuse Potential and Toxicology of Gamma hydroxybutyrate. 4 Hydroxybutyric Aciduria. Gamma Hydroxybutyrate and Oxidative Stress. The Role of Gamma hydroxybutyrate in Brain Function.
Metabolism and Distribution of Gamma Hydroxybutyrate in the Brain. The Gamma hydroxybutyrate Receptor in the Brain. Part of the Pharmacological Actions of Gamma hydroxybutyrate Are Mediated by GABAB Receptors. Membrane Transport of Gamma hydroxybutyrate. Action of Gamma hydroxybutyrate on Neuronal Excitability and Underlying Membrane Conductances. Regulation of Central Dopamine by Gamma hydroxybutyrate. Effects of Gamma hydroxybutyrate on Sleep. Gamma hydroxybutyrate and Absence Seizure Activity. Behavioral Pharmacology of Gamma hydroxybutyrate. Therapeutic Uses of Gamma hydroxybutyrate. Abuse Potential and Toxicology of Gamma hydroxybutyrate. 4 Hydroxybutyric Aciduria. Gamma Hydroxybutyrate and Oxidative Stress. The Role of Gamma hydroxybutyrate in Brain Function.
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