43,99 €
inkl. MwSt.
Versandkostenfrei*
Versandfertig in 1-2 Wochen
payback
22 °P sammeln
  • Broschiertes Buch

All the formulations were prepared by direct compression method. The prepared tablets of all the formulations were evaluated for physical characters, assay, in-vitro drug release, swelling index, hardness and friability. The main aim was to optimize the formulation for 1-12 hours in-vitro release. Optimized formulation F9 containing chitosan and xanthan gum in 1:1 ratio shows better drug release up to 12hours was consider as the best product with respect to in-vitro drug release for 12 hours release action and improved site-specific action. The results showed that the drug release rate was…mehr

Produktbeschreibung
All the formulations were prepared by direct compression method. The prepared tablets of all the formulations were evaluated for physical characters, assay, in-vitro drug release, swelling index, hardness and friability. The main aim was to optimize the formulation for 1-12 hours in-vitro release. Optimized formulation F9 containing chitosan and xanthan gum in 1:1 ratio shows better drug release up to 12hours was consider as the best product with respect to in-vitro drug release for 12 hours release action and improved site-specific action. The results showed that the drug release rate was decreased as the viscosity of the polymer was increased. The drug release kinetics was performed for the optimized formulation and it shows zero order with super case II transport drug release.
Hinweis: Dieser Artikel kann nur an eine deutsche Lieferadresse ausgeliefert werden.
Autorenporträt
Dr. Y. Srinivasa Rao completed B.Pharm, M.Pharm and Ph.D. from A.U. and PDF in KPU, Japan. He received the Best Research Paper Award 4 times by Andhra University. He received the "YOUNG  SCIENTIST AWARD-2016" by CEGR, New Delhi. His write-ups near about 150 Research Paper Publications in National and  International journals.