HIV/AIDS is a major scourge throughout the world, particularly in the DR Congo, and in many hospitals and health centres 80% of hospitalization and mortality rates are linked to this pandemic. HIV/AIDS is a disease that carries a heavy social and economic burden in DR Congo. The female sex was dominant compared to the male (286 female cases against 135 male cases). After analysing the results in our possession, we can say that there is a possibility of transmitting the virus because not all of the PVV is safe. This means that the follow-up of People Living with HIV at a distance does not limit the rate of transmission of HIV/AIDS infection to healthy people. This book is intended for the community, media professionals, publishing partners and funders, students and researchers, and academics. The study aims to guide the necessary process of monitoring and clinical management of PLWHA.