Acute coronary syndrome (ACS) is increasingly prevalent among young patients, particularly in the South Asian region. Young women with ACS undergoing percutaneous coronary intervention (PCI) usually experience greater short-term adverse events than young men, particularly vascular complications and bleeding. However, there is a scarcity of data on the short-term adverse outcomes between young Bangladeshi males and females with ACS undergoing PCI. This study was conducted to compare the short-term outcomes of PCI between young male and female Bangladeshis presenting with ACS.