Genetic studies of IgA nephropathy and Lupus nephritis - Vuong, Mai T.
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The most important finding in these studies is the significant association between the low levels of sCD89-IgA complex in sera of IgA nephropathy patients and the progression of severe IgA nephropathy. One of our studies is the first investigation of the importance of IRF5, STAT4 and TRAF1-C5 gene polymorphisms in patients with IgA nephropathy and showed no evidence of an association of these genes with the development of IgA nephropathy or Lupus nephritis. The results did not suggest any overlap of genetic risk factors in the two diseases, even demonstrated a contrast between IgA nephropathy and Lupus nephritis.…mehr

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Produktbeschreibung
The most important finding in these studies is the significant association between the low levels of sCD89-IgA complex in sera of IgA nephropathy patients and the progression of severe IgA nephropathy. One of our studies is the first investigation of the importance of IRF5, STAT4 and TRAF1-C5 gene polymorphisms in patients with IgA nephropathy and showed no evidence of an association of these genes with the development of IgA nephropathy or Lupus nephritis. The results did not suggest any overlap of genetic risk factors in the two diseases, even demonstrated a contrast between IgA nephropathy and Lupus nephritis.
Autorenporträt
From 1991-1997 I studied at medical school, followed by four years training as a hospital resident physician and has been working as a nephrologist in Vietnam. 2005-2010, I have done PhD project about genetics in the area of nephrology with special focus on IgA nephropathy and Lupus nephritis in Karolinska Institutet, Stockholm, Sweden.