Andere Kunden interessierten sich auch für
![Rett Syndrome mutations: molecular alterations at neuronal synapses]( "Rett Syndrome mutations: molecular alterations at neuronal synapses")
Rett Syndrome mutations: molecular alterations at neuronal synapses32,99 €![Relation of some gene polymorphisms with metabolic syndrome in women]( "Relation of some gene polymorphisms with metabolic syndrome in women")
Relation of some gene polymorphisms with metabolic syndrome in women27,99 €![Down Syndrome in Oman]( "Down Syndrome in Oman")
Down Syndrome in Oman34,99 €![Positional Cloning for Kallmann and Potocki-Shaffer Syndrome]( "Positional Cloning for Kallmann and Potocki-Shaffer Syndrome")
Positional Cloning for Kallmann and Potocki-Shaffer Syndrome36,99 €![Hormonal key players for obesity in Children with Down Syndrome]( "Hormonal key players for obesity in Children with Down Syndrome")
Hormonal key players for obesity in Children with Down Syndrome46,99 €![Engelmann syndrome]( "Engelmann syndrome")
Engelmann syndrome22,99 €![Bardet Biedl Syndrome]( "Bardet Biedl Syndrome")
Bardet Biedl Syndrome25,99 €
Down Syndrome (DO) is a genetic syndrome caused by an excess of genetic material on chromosome 21, causing the individual to have three chromosomes 21 instead of two. The general objective of this study was to describe the factors involved in the predisposition of children with Down Syndrome to develop Acute Megacaryoblastic Leukemia (AML-M7). The methodology used is a literature review in narrative format. The SD present congenital characteristics such as mental retardation, muscle weakness, cardiac anomaly, among others. These patients also have an increased risk of developing leukemia. On the other hand, children with SD have a lower risk of developing solid tumors. This leukemogenic condition in SD arouses interest in the study of these pathologies, as experiments suggest that children with trisomy 21 have a 20 times higher chance of developing leukemias than other children, especially LMA-M7. Genetic and molecular studies have shown that this increased likelihood of SD to develop leukaemia is due to the presence of somatic mutations in Gene GATA1.
Hinweis: Dieser Artikel kann nur an eine deutsche Lieferadresse ausgeliefert werden.
Hinweis: Dieser Artikel kann nur an eine deutsche Lieferadresse ausgeliefert werden.