Genome Editing for Neurodegenerative Diseases: From Concept to Clinical Trials examines recent advances in neurodegenerative disease research and clinical challenges in practical applications. With an emphasis on genome editing tools such as ZFNs, TALENSs and CRISPR-Cas, this book sheds light on the possibilities to counteract genetic and neurodegenerative diseases. It will be of interest to researchers in neuroscience and biopharmaceuticals, as well as clinicians specializing in neurodegenerative diseases.
Genome Editing for Neurodegenerative Diseases: From Concept to Clinical Trials examines recent advances in neurodegenerative disease research and clinical challenges in practical applications. With an emphasis on genome editing tools such as ZFNs, TALENSs and CRISPR-Cas, this book sheds light on the possibilities to counteract genetic and neurodegenerative diseases. It will be of interest to researchers in neuroscience and biopharmaceuticals, as well as clinicians specializing in neurodegenerative diseases.Hinweis: Dieser Artikel kann nur an eine deutsche Lieferadresse ausgeliefert werden.
Introduction Burkhard Poeggeler 1. Overview of genome editing tools and general neurodegenerative diseases Anand Singh, Ankur Kumar, Nandigam Pardhipa, Sachin G. Swami and Vibha Dwivedi 2. Genetic and molecular basis of neurodegenerative diseases Amit Singh and Sandeep K. Singh 3. Genome editing tools: Principles, structures and mechanisms Rayees Ahmad Naik, Mehak Naseer Mir, Roshni Rajpoot, Sonalika Singh, Kusum Singh and Sandeep K. Singh 4. Advances in CRISPER/Cas System and Genome Editing Technologies for the Treatment of Neurodegenerative Diseases Sandeep K. Singh, Shailendra Kumar Mishra, Hung-Ming Chang and Ahmed Obaid 5. Use of CRISPR systems in genetic screening to investigate neurodegenerative diseases Dr. Koyel Kar and Sandeep K. Singh 6. Epigenetic manipulation and genes regulation using CRISPR/Cas system for neurodegenerative diseases Josephine Esposto 7. Transgene delivery systems: Viral, non-viral and other methods for CNS Umesh Kumar, Bhupender Sahu and Bibhudendu Behera 8. Gene-therapies for neurodegenerative diseases: current knowledge and challenges Umesh Kumar, Bhumi Arora, Sakshi Garg, Aditya Shrivastav, Mrinalini Sharma and Bhupender Sahu 9. Gene therapies under clinical trials for neurodegenerative diseases Umesh Kumar 10. Clinical challenges and future prospective in use of gene-editing tools as neurotherapeutics Burkhard Poeggeler
Introduction Burkhard Poeggeler 1. Overview of genome editing tools and general neurodegenerative diseases Anand Singh, Ankur Kumar, Nandigam Pardhipa, Sachin G. Swami and Vibha Dwivedi 2. Genetic and molecular basis of neurodegenerative diseases Amit Singh and Sandeep K. Singh 3. Genome editing tools: Principles, structures and mechanisms Rayees Ahmad Naik, Mehak Naseer Mir, Roshni Rajpoot, Sonalika Singh, Kusum Singh and Sandeep K. Singh 4. Advances in CRISPER/Cas System and Genome Editing Technologies for the Treatment of Neurodegenerative Diseases Sandeep K. Singh, Shailendra Kumar Mishra, Hung-Ming Chang and Ahmed Obaid 5. Use of CRISPR systems in genetic screening to investigate neurodegenerative diseases Dr. Koyel Kar and Sandeep K. Singh 6. Epigenetic manipulation and genes regulation using CRISPR/Cas system for neurodegenerative diseases Josephine Esposto 7. Transgene delivery systems: Viral, non-viral and other methods for CNS Umesh Kumar, Bhupender Sahu and Bibhudendu Behera 8. Gene-therapies for neurodegenerative diseases: current knowledge and challenges Umesh Kumar, Bhumi Arora, Sakshi Garg, Aditya Shrivastav, Mrinalini Sharma and Bhupender Sahu 9. Gene therapies under clinical trials for neurodegenerative diseases Umesh Kumar 10. Clinical challenges and future prospective in use of gene-editing tools as neurotherapeutics Burkhard Poeggeler
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