Aging affects neurological function leading to neurological disease As society grows older, so do the neurological problems associated with aging. These can be new neurological deficits due to the aging process itself, or the effect of aging on already existing neurological conditions. Neurologists will spend increasing amounts of time managing patients with age-related neurological complications. Geriatric Neurology brings together the wisdom of world-leading experts. They have crafted a new textbook to define this emerging subspecialty from basic science through clinical assessment and…mehr
Aging affects neurological function leading to neurological disease
As society grows older, so do the neurological problems associated with aging. These can be new neurological deficits due to the aging process itself, or the effect of aging on already existing neurological conditions. Neurologists will spend increasing amounts of time managing patients with age-related neurological complications.
Geriatric Neurology brings together the wisdom of world-leading experts. They have crafted a new textbook to define this emerging subspecialty from basic science through clinical assessment and medical management to social aspects of patient care. Geriatric Neurology covers: The aging brain in neurology Assessment of the geriatric neurology patient Neurological conditions in the elderly Therapeutics for the geriatric neurology patient Management issues beyond therapeutics
Comprehensive in scope but with practical focus for effective patient care, Geriatric Neurology provides top-of-class guidance for the management of elderly patients with neurological disorders.
Anil K. Nair, MD, Director, Alzheimers Disease Center, Quincy Medical Center, Quincy, MA, USA. Marwan N. Sabbagh, MD, Director, Banner Sun Health Research Institute and Research Professor of Neurology, University of Arizona College of Medicine, Phoenix AZ, USA.
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About the Editors vii List of Contributors viii Preface xii Acknowledgments xiii Part 1 The Aging Brain in Neurology 1 1 The Biology of Aging: Implications for Diseases of Aging and Health Care in the Twenty-First Century 3 Douglas F. Watt 2 Functional Changes Associated with the Aging Nervous System 38 Julie A. Schneider and Chunhui Yang Part 2 Assessment of the Geriatric Neurology Patient 69 3 Approach to the Geriatric Neurology Patient: The Neurologic Examination 71 Marwan N. Sabbagh and Anil K. Nair 4 Assessment of Cognitive Status in Geriatric Neurology 85 4.1 Mental Status Examination in the Geriatric Neurology Patient 87 Papan Thaipisuttikul and James E. Galvin 4.2 Neuropsychology in Geriatric Neurology 98 Donald J. Connor and Marc A. Norman 5 Cognitive Reserve and the Aging Brain 118 Adrienne M. Tucker and Yaakov Stern 6 Gait Disorders in the Graying Population 126 Joe Verghese and Jessica Zwerling 7 Imaging of the Geriatric Brain 136 7.1 Structural Neuroimaging in Degenerative Dementias 138 Liana G. Apostolova 7.2 Functional Imaging in Dementia 146 Adam S. Fleisher and Alexander Drzezga 7.3 Amyloid Imaging 162 Anil K. Nair and Marwan N. Sabbagh 8 Clinical Laboratory Investigations in Geriatric Neurology 170 Geoffrey S. Baird and Thomas J. Montine Part 3 Neurologic Conditions in the Elderly 181 9 Cognitive Impairment and the Dementias 183 9.1 Mild Cognitive Impairment 187 Ranjan Duara Miriam Jocelyn Rodriguez and David A. Loewenstein 9.2 Alzheimer's Disease 200 Martin R. Farlow 9.3 Dementia with Lewy Bodies 208 Clive Ballard 9.4 Vascular Cognitive Impairment 224 Helena C. Chui and Freddi Segal-Gidan 9.5 Frontotemporal Dementia 239 David Perry and Howard Rosen 9.6 Primary Progressive Aphasia 251 Maya L. Henry Stephen M. Wilson and Steven Z. Rapcsak 9.7 Prion Diseases 267 Michael D. Geschwind and Katherine Wong 9.8 Normal Pressure Hydrocephalus 281 Norman R. Relkin 10 Depression in the Elderly: Interactions with Aging Stress Chronic Pain Infl ammation and Neurodegenerative Disorders 287 Douglas F. Watt 11 Cerebrovascular Diseases in Geriatrics 302 Patrick Lyden Khalil Amir and Ilana Tidus 12 Movement Disorders 313 12.1 Parkinson's Disease 315 Robert Fekete and Joseph Jankovic 12.2 Essential Tremor and Other Tremor Disorders 325 Holly Shill 12.3 Progressive Supranuclear Palsy 333 Virgilio Gerald H. Evidente 12.4 Corticobasal Degeneration 344 Katrina Gwinn 13 Sleep Disorders 347 Sanford Auerbach 14 Autonomic Dysfunction and Syncope 358 Rohit R. Das 15 Geriatric Epilepsy 370 David V. Lardizabal 16 Vertigo and Dizziness in the Elderly 379 Terry D. Fife and Salih Demirhan 17 Disorders of the Special Senses in the Elderly 396 Douglas J. Lanska 18 Nervous System Infections 460 Ronald Ellis David Croteau and Suzi Hong 19 Delirium 478 Alan Lerner Stefani Parrisbalogun and Joseph Locala 20 Headache in the Elderly 486 Brian McGeeney 21 Neuromuscular Disorders 494 Heber Varela and Clifton Gooch Part 4 Therapeutics for the Geriatric Neurology Patient 519 22 Neurosurgical Care of the Geriatric Patient 521 David Fusco Rasha Germain and Peter Nakaji 23 Treatment of Dementia 556 23.1 Evidence-Based Pharmacologic Treatment of Dementia 557 Jasmeet Singh Marwan N. Sabbagh and Anil K. Nair 23.2 Immunotherapy for Alzheimer's Disease 574 Michael Grundman Gene G. Kinney Eric Yuen and Ronald Black 24 Geriatric Psychopharmacology 586 Sandra A. Jacobson 25 Nonpharmacologic Treatment of Behavioral Problems in Persons with Dementia 615 Gary A. Martin and John Ranseen 26 Expressive Art Therapies in Geriatric Neurology 630 Daniel C. Potts Bruce L. Miller Carol A. Prickett Andrea M. Cevasco and Angel C. Duncan Part 5 Important Management Issues Beyond Therapeutics in the Geriatric Neurology Patient 645 27 Dietary Factors in Geriatric Neurology 647 Yian Gu and Nikolaos Scarmeas 28 Exercising the Brain: Nonpharmacologic Interventions for Cognitive Decline Associated with Aging and Dementia 669 Brenna A. Cholerton Jeannine Skinner and Laura D. Baker 29 Driving Impairment in Older Adults 682 Anne D. Halli-Tierney and Brian R. Ott 30 Elder Abuse and Mistreatment 699 Elliott Schulman Ashley Roque and Anna Hohler 31 Advocacy in Geriatric Neurology 707 Glenn Finney and Anil K. Nair Index 713 Color plate section appears between pages 50 and 5
About the Editors vii List of Contributors viii Preface xii Acknowledgments xiii Part 1 The Aging Brain in Neurology 1 1 The Biology of Aging: Implications for Diseases of Aging and Health Care in the Twenty-First Century 3 Douglas F. Watt 2 Functional Changes Associated with the Aging Nervous System 38 Julie A. Schneider and Chunhui Yang Part 2 Assessment of the Geriatric Neurology Patient 69 3 Approach to the Geriatric Neurology Patient: The Neurologic Examination 71 Marwan N. Sabbagh and Anil K. Nair 4 Assessment of Cognitive Status in Geriatric Neurology 85 4.1 Mental Status Examination in the Geriatric Neurology Patient 87 Papan Thaipisuttikul and James E. Galvin 4.2 Neuropsychology in Geriatric Neurology 98 Donald J. Connor and Marc A. Norman 5 Cognitive Reserve and the Aging Brain 118 Adrienne M. Tucker and Yaakov Stern 6 Gait Disorders in the Graying Population 126 Joe Verghese and Jessica Zwerling 7 Imaging of the Geriatric Brain 136 7.1 Structural Neuroimaging in Degenerative Dementias 138 Liana G. Apostolova 7.2 Functional Imaging in Dementia 146 Adam S. Fleisher and Alexander Drzezga 7.3 Amyloid Imaging 162 Anil K. Nair and Marwan N. Sabbagh 8 Clinical Laboratory Investigations in Geriatric Neurology 170 Geoffrey S. Baird and Thomas J. Montine Part 3 Neurologic Conditions in the Elderly 181 9 Cognitive Impairment and the Dementias 183 9.1 Mild Cognitive Impairment 187 Ranjan Duara Miriam Jocelyn Rodriguez and David A. Loewenstein 9.2 Alzheimer's Disease 200 Martin R. Farlow 9.3 Dementia with Lewy Bodies 208 Clive Ballard 9.4 Vascular Cognitive Impairment 224 Helena C. Chui and Freddi Segal-Gidan 9.5 Frontotemporal Dementia 239 David Perry and Howard Rosen 9.6 Primary Progressive Aphasia 251 Maya L. Henry Stephen M. Wilson and Steven Z. Rapcsak 9.7 Prion Diseases 267 Michael D. Geschwind and Katherine Wong 9.8 Normal Pressure Hydrocephalus 281 Norman R. Relkin 10 Depression in the Elderly: Interactions with Aging Stress Chronic Pain Infl ammation and Neurodegenerative Disorders 287 Douglas F. Watt 11 Cerebrovascular Diseases in Geriatrics 302 Patrick Lyden Khalil Amir and Ilana Tidus 12 Movement Disorders 313 12.1 Parkinson's Disease 315 Robert Fekete and Joseph Jankovic 12.2 Essential Tremor and Other Tremor Disorders 325 Holly Shill 12.3 Progressive Supranuclear Palsy 333 Virgilio Gerald H. Evidente 12.4 Corticobasal Degeneration 344 Katrina Gwinn 13 Sleep Disorders 347 Sanford Auerbach 14 Autonomic Dysfunction and Syncope 358 Rohit R. Das 15 Geriatric Epilepsy 370 David V. Lardizabal 16 Vertigo and Dizziness in the Elderly 379 Terry D. Fife and Salih Demirhan 17 Disorders of the Special Senses in the Elderly 396 Douglas J. Lanska 18 Nervous System Infections 460 Ronald Ellis David Croteau and Suzi Hong 19 Delirium 478 Alan Lerner Stefani Parrisbalogun and Joseph Locala 20 Headache in the Elderly 486 Brian McGeeney 21 Neuromuscular Disorders 494 Heber Varela and Clifton Gooch Part 4 Therapeutics for the Geriatric Neurology Patient 519 22 Neurosurgical Care of the Geriatric Patient 521 David Fusco Rasha Germain and Peter Nakaji 23 Treatment of Dementia 556 23.1 Evidence-Based Pharmacologic Treatment of Dementia 557 Jasmeet Singh Marwan N. Sabbagh and Anil K. Nair 23.2 Immunotherapy for Alzheimer's Disease 574 Michael Grundman Gene G. Kinney Eric Yuen and Ronald Black 24 Geriatric Psychopharmacology 586 Sandra A. Jacobson 25 Nonpharmacologic Treatment of Behavioral Problems in Persons with Dementia 615 Gary A. Martin and John Ranseen 26 Expressive Art Therapies in Geriatric Neurology 630 Daniel C. Potts Bruce L. Miller Carol A. Prickett Andrea M. Cevasco and Angel C. Duncan Part 5 Important Management Issues Beyond Therapeutics in the Geriatric Neurology Patient 645 27 Dietary Factors in Geriatric Neurology 647 Yian Gu and Nikolaos Scarmeas 28 Exercising the Brain: Nonpharmacologic Interventions for Cognitive Decline Associated with Aging and Dementia 669 Brenna A. Cholerton Jeannine Skinner and Laura D. Baker 29 Driving Impairment in Older Adults 682 Anne D. Halli-Tierney and Brian R. Ott 30 Elder Abuse and Mistreatment 699 Elliott Schulman Ashley Roque and Anna Hohler 31 Advocacy in Geriatric Neurology 707 Glenn Finney and Anil K. Nair Index 713 Color plate section appears between pages 50 and 5
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