Malignant glial tumors, especially glioblastoma multiforme, cause devastating consequences for both patients and their families. Despite newly developed surgical techniques and technologies, and also new chemotherapeutics, survival rates for malignant glial tumors are still in undesirable levels. When looked from neurosurgical perspective, for most of the neurosurgeons, patients with malignant gliomas are all candidates of surgical excision. In this book, our aim is to provide a neurosurgical perspective to the one of the most compulsive issues of the modern neurooncology.