Does operating on the global stage change the nature of leadership? Is cultural intelligence essential to global leadership success? And how can we use neuroscience to establish and identify global leadership competencies and their development? This dissertation takes a deep dive into these topics. By interviewing experts in management, cultural and emotional intelligence and neuroscience, this paper concludes that there are developmental opportunities to grow global leaders. Leading research on the effects of Transcendental Meditation and other interventions that transform brain behavior can make leaders and managers more emotionally mature, culturally sensitive and globally aware. The revelation that leaders impact their followers merely through a 'mirror neuron' effect points to the criticality of leader development. If you are wondering what makes a global leader and how we can develop them, this is an essential read.