Adina Glodeanu, Maria For_ofoiu. Mircea C. For_ofoiu, Diana Cherata

Gls Analysis for Identification the Right Ventricular Disfunction

Gls Analysis for Identification the Right Ventricular Disfunction in Patients With Cancer Therapy-related Lv Dysfunction

• Broschiertes Buch

Produktbeschreibung

Background: This study was designed to assess right ventricular (RV) systolic function in cancer patients. Methods and Results: Left ventricle (LV) and free-wall RV longitudinal strain were analysed prior and after 6 months of treatment (at 68 patients), using a vendor-independent software, together with left ventricular ejection fraction (LVEF), tricuspid annulus plane systolic excursion and RV fractional area change. Cancer therapy-related cardiac dysfunction was defined as a LVEF drop of >10% to <53%. Both LVEF fraction (59±7% vs. 55±8%, p<0.0001) and LV longitudinal strain (-19.7±2.5% vs. -17.1±2.6%, p<0.0001) were reduced.Cancer therapy-related cardiac dysfunction was detected in 20 patients (29%). In 15 out of these 20 patients (75%), a concomitant relative reduction in free-wall RV longitudinal strain magnitude by 17±7% was detected. A relative drop of RV longitudinal strain >17% had a sensitivity of 55% and a specificity of 70% to identify patients with cancer treatment. Conclusions: GLS analysis allows the identification of subclinical RV dysfunction appearing in the course of cancer treatment when conventional indices of RV dysfunction function are unaffected.

Produktdetails

• Verlag: LAP Lambert Academic Publishing
• Seitenzahl: 52
• Erscheinungstermin: 8. August 2022
• Englisch
• Abmessung: 220mm x 150mm x 4mm
• Gewicht: 96g
• ISBN-13: 9786205490761
• ISBN-10: 6205490765
• Artikelnr.: 65443833

Autorenporträt

A.Glodeanu, M.For¿ofoiu, M.C.For¿ofoiu: Berufliche Tätigkeit in Forschung und Lehre an der Universität für Medizin und Pharmazie; D.Cherata - Mitglied der Europäischen Vereinigung für kardiovaskuläre Bildgebung.Die Autoren sind Doktor der medizinischen Wissenschaften an der Universität für Medizin und Pharmazie in Craiova. Schwerpunkt: alltägliche Forschung, medizinische Tätigkeit in der Kardiologie.