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Odnoj iz naibolee interesnyh grupp klassa proteoliticheskih fermentov yavlyajutsya serinovye proteinazy bacill. Jeti belki uchastvujut v adaptacionnyh processah v usloviyah stressa, sporoobrazovanii i prorastanii spor. Neoslabevajushhij interes k jetim fermentam obuslovlen shirotoj ih prakticheskogo primeneniya. Vydeleny proteinazy bacill, obladajushhie fibrinoliticheskimi i tromboliticheskimi svojstvami. V svyazi s rostom chisla zabolevanij, svyazannyh s tromboobrazovaniem, aktual'nym yavlyaetsya poisk novyh fermentov s vysokoj aktivnost'ju, specifichnost'ju i nizkoj toxichnost'ju. Odnoj iz podgrupp serinovyh proteinaz yavlyajutsya glutamiljendopeptidazy, obladajushhie uzkoj substratnoj specifichnost'ju. Pojetomu oni yavlyajutsya vysokotochnymi "instrumentami" dlya fragmentacii belkovyh molekul pri issledovanii pervichnoj struktury. Poskol'ku bacilly sekretirujut razlichnye proteinazy, vydelenie individual'nyh belkov kontaminiruet s belkovymi primesyami, kotorye zatrudnyajut analiticheskie oshibki issledovaniya fermenta. Genno-inzhenernye metody pozvolyajut sozdavat' rekombinantnye shtammy, soderzhashhie na plazmide gen individual'nogo fermenta, chto perspektivno dlya razrabotki sposobov polucheniya gomogennyh proteinaz.