Jose Vina

Glutathione (1990)

• Broschiertes Buch

Produktbeschreibung

This important book is to present the reader with developments concerning glutathione research. This work focuses on the synthesis-degradation and oxidation-reduction cycles of glutathione, the physiological functions of glutathione (especially in mammalian cells), and the analytical methods used to accurately measure the glutathione status of cells. This resource addresses specific modification of glutathione metabolism that is of special interest in the treatment of some tumors. This rare volume also introduces some different, new techniques on how to accurately measure glutathione, specifically in its oxidized form. Anyone involved with biochemistry, physiology, toxicology, pharmacology, nutrition and radiation biology will find this publication interesting and filled with useful information. It is also a valuable reference for research scientists in such fields as aging, metabolism disorders, and glutathione research.

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Produktdetails

• Verlag: CRC Press
• Seitenzahl: 394
• Erscheinungstermin: 28. Januar 2019
• Englisch
• Abmessung: 254mm x 178mm x 21mm
• Gewicht: 739g
• ISBN-13: 9781138558939
• ISBN-10: 1138558931
• Artikelnr.: 56929018

Autorenporträt

Jose Vina

Inhaltsangabe

1. Publications on Glutathione, 1983-1987, A Bibliometric Study 2.
Determination of Tissue Glutathione 3. Manipulation of Liver Glutathione
Status-A Double-Edged Sword 4. Compartmentation of Cellular Glutathione in
Mitochondrial and Cytosolic Pools 5. Hormonal Influence of GSH Content in
Isolated Hepatocytes 6. Glutathione Transport and Its Significance in
Oxidative Stress 7. Glutathione and Alcohol. Glutathione in Prokaryotes 8.
Biosynthesis and Regulation of g-Glutamyl Transpeptidase 9. The Role of
g-Glutamyl Transpeptidase (g GTPase) in Mammary Tissue 10. Structure,
Mechanism, Functions, and Regulatory Properties of Glutathione Reductase
11. Glutathione Transferase in Human Tumors and Human Cancer Cell Lines 12.
The Formation of Disulphide Bonds in the Synthesis of Secretory Proteins:
Properties and Role of Protein Disulfide-Isomerase 13. The Glyoxalase
System: Towards Functional Characterization and a Role in Disease Processes
14. Glutaredoxin: Structure and Function 15. Glutathione and Protein
Function 16. Role of Glutathione in the Regulation of Protein Synthesis and
Degradation in Eukaryotes 17. Aging and Increased Oxidation of the Sulfur
Pool 18. Glutathione Metabolism in the Mammalian Ocular Lens 19. Role of
Glutathione in the Aging Process of the Lens 20. Renal Handling of
Glutathione 21. Glutathione in Ischemia and Reperfusion-Induced Tissue
Injury 22. Free Radicals and Thiol Compounds (The Role of Glutathione
against Free Radical Toxicity) 23. N-Acetylcysteine Stereoisomers as in
vivo Probes of the Role of Glutathione in Drug Detoxification 24.
Glutathione Levels in Human Hepatocytes Exposed to Paracetamol 25.
Biological Implications of the Nucleophilic Addition of Glutathione to
Quinoid Compounds 26. Glutathione and Hepatobiliary Transport of
Xenobiotics 27. The Role of Glutathione in the Enzymatic Deiodination of
Thyroid Hormone 28. Glutathione in Pineal Mechanisms and Functions 29.
Nutritional Significance of Glutathione 30. The Potential Benefits of
Dietary Glutathione on Immune Function and Other Practical Implications 31.
Hereditary Disorders in Glutathione Metabolism.