Gluten Intolerance: From Childhood to Adulthood - Manouni, Chafika; Batouche, Djamila-Djahida; Batouche, Djilali
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Celiac disease (CD) is an autoimmune disease characterized in its classic form by total or subtotal villous atrophy secondary to gluten ingestion. The genetic predisposition of this disease is important since 95% of patients with this disease present a class II HLA of type DQ2 or DQ8. It has been the subject of renewed interest in recent years due to its high frequency and highly polymorphic symptomatology. It is a condition that is very frequently avoided in our country.The objectives of our study were to find out the evolutionary genius of celiac disease evolving from childhood to adulthood,…mehr

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Produktbeschreibung
Celiac disease (CD) is an autoimmune disease characterized in its classic form by total or subtotal villous atrophy secondary to gluten ingestion. The genetic predisposition of this disease is important since 95% of patients with this disease present a class II HLA of type DQ2 or DQ8. It has been the subject of renewed interest in recent years due to its high frequency and highly polymorphic symptomatology. It is a condition that is very frequently avoided in our country.The objectives of our study were to find out the evolutionary genius of celiac disease evolving from childhood to adulthood, to determine the frequency of associated dysimmune disorders encountered in our population, to search for complications in our patients and even to carry out a biological, morphological, behavioural and sociological investigation.Our results revealed a late age of diagnosis in childhood, a clear increase in the frequency of dysimmune disorders associated with a predilection for insulin-dependent diabetes and autoimmune hepatopathies in our population.
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Autorenporträt
Pr MANOUNI: Director del Departamento de Medicina de Orán; Presidente del comité pedagógico regional de especialidad; Presidente nacional de graduación de la revisión de los estudios médicos de la Facultad de Medicina de Orán; Miembro del consejo científico de la Facultad de Medicina de Orán; Jefe interino del Departamento de Hepato-Gastro-Enterología EHU ORAN.