Vietnam is reckoned one of some countries most severely affected by climate change, and the Mekong River Delta in the South of Vietnam is one of three deltas most vulnerable to sea level rise. Climate change has increasingly shown its existence, especially through the rise of natural disasters that cause big human and property losses to this area. Further, the rapid population growth has resulted in a very high pressure on the natural resources of the inland and coastal areas which were of very high biological diversity. This book presents the awareness of key stakeholders of provinces in Mekong Delta region. The results show that local people and officials have different perception about the impacts of climate change.