Aim of this work is to verify the state of the art related the use of graphene and its derivates in some vaccine technology (m RNA), to show the chemical properties of this kind of carriers (or extractive agent) and to list the evidence at today related peculiarity involved in some covid-19 vaccine. The researcher will produce their own opinion about this topic.Of great relevance to verify the manufacturing procedure of this innovative product:(m- Rna vaccine) and the technology and material used in purification phases.(quality of the raw materials used and procedures).Observing the fact that every year various registered and authorized drugs are recalled by the public regulatory agency (in example last Ranitidin cases due by the possibility of impurity presence of a cancerogenic suntans) it is interesting to observe the innovative production strategy of some m RNA vaccine.