Growth Hormone Deficiency in Adults
Galina Götherström
Broschiertes Buch

Growth Hormone Deficiency in Adults

Long-term effects of Growth Hormone Replacement Therapy

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Deficiency of growth hormone in adults results in abnormal body composition, mainly increased fat mass and decreased lean body mass, reduced bone mass and muscle strength, increased cardiovascular morbidity and mortality. Short-term growth hormone replacement reverses many of the symptoms associated with adult growth hormone deficiency. The effects and the safety of long-term growth hormone replacement therapy in adults are unknown. The aim of this thesis was to investigate the efficacy and the safety of 5-10-year growth hormone replacement in a large group of patients with adult onset of grow...