Rameshwar K. Sharma (Hrsg.)

Guanylate Cyclase

Herausgeber: Sharma, Rameshwar K.

• Gebundenes Buch

Produktbeschreibung

From somewhat enigmatic beginnings 40 years ago, guanylate cyclase research has emerged to occupy a position of prominence in the study of signal transduction. Guanylate cyclase has several intriguing features, including existence in two major forms, membrane and soluble, each independently regulated by distinct mechanisms. The membrane form gives rise to a fascinating signal transduction story important to both peptide hormones and sensory neurons. This volume covers the evolution of the field, peptide hormone receptor work, membrane guanylate cycles, related retinal diseases, and the biochemistry and physiology of the soluble form. The 16 chapters are written by leaders in the field.

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Produktdetails

• Developments in Molecular and Cellular Biochemistry 36
• Verlag: Springer Netherlands
• 2002
• Seitenzahl: 200
• Erscheinungstermin: 31. März 2002
• Englisch
• Abmessung: 303mm x 215mm x 17mm
• Gewicht: 1576g
• ISBN-13: 9780792376828
• ISBN-10: 079237682X
• Artikelnr.: 21831191

Inhaltsangabe

Evolution of the membrane guanylate cyclase transduction system.
Biochemistry and physiology of the natriuretic peptide receptor guanylyl cyclases.
Natriuretic peptide receptor: Structure and signaling.
Intracellular trafficking and metabolic turnover of ligand
bound guanylyl cyclase/atrial natriuretic peptide receptor
A into subcellular compartments.
Structure and function of the heat
stable enterotoxin receptor/guanylyl cyclase C.
Ultracytochemistry as a tool for the study of the cellular and subcellular localization of membrane
bound guanylate cyclase (GC) activity. Applicability to both receptor
activated and receptor
independent GC activity.
Photoreceptor specific guanylate cyclases in vertebrate phototransduction.
Calcium
modulated membrane guanylate cyclase in synaptic transmission?.
Calcium
sensitive ROS
GC1 signaling outside of photoreceptors: A common theme.
A novel role of RGS9. Inhibition of retinal guanylyl cyclase.
Retinal diseases linked with photoreceptor guanylate cyclase.
Factors that affect regulation of cGMP synthesis in vertebrate photoreceptors and their genetic link to human retinal degeneration.
Guanylyl cyclases in unicellular organisms.
Isoforms of NO
sensitive guanylyl cyclase.
The receptor
like properties of nitric oxide
activated soluble guanylyl cyclase in intact cells.
Soluble guanylate cyclases in the retina.
Index to Volume 230.