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This introductory book details reliable approaches to problems met in standard microarray data analyses. Providing examples of established approaches such as cluster analysis, function prediction, and principle component analysis, this book offers real examples to illustrate the key concepts of data analysis.
Written for biologists and medical researchers who don't have any special training in data analysis and statistics, Guide to Analysis of DNA Microarray Data, Second Edition begins where DNA array equipment leaves off: the image produced by the microarray. The text deals with the
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Produktbeschreibung
This introductory book details reliable approaches to problems met in standard microarray data analyses. Providing examples of established approaches such as cluster analysis, function prediction, and principle component analysis, this book offers real examples to illustrate the key concepts of data analysis.
Written for biologists and medical researchers who don't have any special training in data analysis and statistics, Guide to Analysis of DNA Microarray Data, Second Edition begins where DNA array equipment leaves off: the image produced by the microarray. The text deals with the questions that arise starting at this point, providing an introduction to microarray technology, then moving on to image analysis, data analysis, cluster analysis, and beyond.
With all chapters rewritten, updated, and expanded to include the latest generation of technology and methods, Guide to Analysis of DNA Microarray Data, Second Edition offers practitioners reliable information using concrete examples and a clear, comprehensible style. This Second Edition features entirely new chapters on:
_ Image analysis
_ Experiment design
_ Automated analysis, integrated analysis, and systems biology
_ Interpretation of results
Intended for readers seeking practical applications, this text covers a broad spectrum of proven approaches in this rapidly growing technology. Additional features include further reading suggestions for each chapter, as well as a thorough review of available analysis software.
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Autorenporträt
Steen Knudsen received his Ph.D. from the University of Copenhagen in 1990 and was among the pioneers of bioinformatics with a publication in Nature the same year. His postdoctoral training in bioinformatics at Harvard University concerned computational gene finding in the human genome. Since 1998 he has been working with methods for analysis of DNA microarray data. He currently heads the DNA microarray group at the Technical University of Denmark.
Rezensionen
"Bioinformaticians, statisticians, computer scientists, biologists, and medical researchers will find this well written book extremely useful." ( Journal of Statistical Computation and Simulation , September 2005)
"...useful for anybody who wants to catch up with the marvels of modern laboratory technology..." ( Chemistry & Industry , 17th January 2005)

"This book would be useful for anyone working with the DNA microarray technology." ( Annals of Biomedical Engineering , November 2004)

"...concisely written with clear illustrations and tables [with]...a good deal of new material." ( E-STREAMS , November 2004)