David R. Sibley / Israel Hanin / Michael Kuhar / Phil Skolnick (eds.)

Handbook of Contemporary Neuropharmacology, 3 Volume Set

Ed. by David R. Sibley, Israel Hanin, Michael J. Kuhar et al.

• Gebundenes Buch

Produktbeschreibung

Written at the professional level, the Handbook of Contemporary Neuropharmacology consists of chapters reviewing basic and advanced topics in neuropharmacology. The scope of the Handbook is heavily pre-clinical, covering mostly basic science topics; however, the chapters are organized under a clinical 'umbrella'.An online version of the Handbook is available on Wiley InterScience.

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A comprehensive, accessible reference for neuropharmacology

Recognizing the central role of neuropharmacology in drug development, therapy, and the potential for developing novel classes of neuropharmacologic agents stemming from current research, prominent experts collaborated to develop this comprehensive, up-to-date reference that consolidates information about the latest approaches and advances in neuropharmacology in general, and in the research and treatment of specific conditions. Edited by leaders in neuropharmacology and featuring chapters by respected authorities in their specialty areas, Handbook of Contemporary Neuropharmacology is an invaluable resource for pharmacologists, neurologists, psychiatrists, pharmaceutical professionals, and students. It covers basic neuropharmacology and then delves into its applications in research and in treating specific disorders:
_ Mood Disorders
_ Anxiety and Stress Disorders
_ Schizophrenia and Psychosis
_ Substance Abuse and Addictive Disorders
_ Pain
_ Sleep and Arousal
_ Development and Developmental Disorders
_ Neurodegenerative and Seizure Disorders
_ Neuroimmunology
_ Eating and Metabolic Disorders

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Hinweis: Dieser Artikel kann nur an eine deutsche Lieferadresse ausgeliefert werden.

Produktdetails

• Verlag: Wiley & Sons
• Artikelnr. des Verlages: 14666053000
• 1. Auflage
• Seitenzahl: 3040
• Erscheinungstermin: 30. März 2007
• Englisch
• Abmessung: 275mm x 210mm x 172mm
• Gewicht: 5570g
• ISBN-13: 9780471660538
• ISBN-10: 0471660531
• Artikelnr.: 22012031

Autorenporträt

DAVID R. SIBLEY, PhD, is a Senior Investigator and Chief of the Molecular Neuropharmacology Section in the National Institute of Neurological Disorders and Stroke, National Institutes of Health. His laboratory is currently investigating the molecular, cellular, and biochemical properties of dopamine receptors and their role in neuronal signaling and pathophysiological states. ISRAEL HANIN, PhD, is Professor and Chair Emeritus in the Department of Pharmacology at Loyola University Chicago. He formerly worked at the National Institute of Mental Health, Laboratory of Preclinical Pharmacology, and at the University of Pittsburgh Department of Psychiatry. Dr. Hanin's research has focused on cholinergic mechanisms, animal models for Alzheimer's disease, and the potential role of glycosaminoglycans in the treatment of Alzheimer's disease. MICHAEL KUHAR, PhD, is currently a Candler Professor and Georgia Research Alliance Professor of Neuropharmacology at the Yerkes Primate Center at Emory University. He previously was a professor in the Neuroscience Department at Johns Hopkins, and a branch chief at the National Institute on Drug Abuse. Dr. Kuhar has published more than 800 articles, abstracts, book chapters, reviews, and patents. PHIL SKOLNICK, PhD, D.Sc. (hon.), is Executive Vice President and Chief Scientific Officer for DOV Pharmaceutical, Inc. He was formerly a Lilly Fellow in Neuroscience and also served as Chief of the Laboratory of Neuroscience, National Institutes of Health.

Inhaltsangabe

Preface.
Contributors.
VOLUME 1.
PART I: BASIC NEUROPHARMACOLOGY.
Chapter 1: Soup or Sparks: The History of Drugs and Synapses (William Van
der Kloot).
Chapter 2: Synaptic Transmission: Intercellular Signaling (J. David Jentsch
and Robert H. Roth).
Chapter 3: Synaptic Transmission: Intracellular Signaling (R. Benjamin
Free, Lisa A. Hazelwood, Yoon Namkung Michele L. Rankin, Elizabeth B. Rex,
and David R. Sibley).
Chapter 4: Neuronal Nicotinic Receptors: One Hundred Years of Progress (
Kenneth J. Kellar and Yingxian Xiao).
Chapter 5: Muscarinic Acetylcholine Receptors (Jürgen Wess).
Chapter 6: Norepinephrine/Epinephrine (Megan E. Kozisek and David B. Bylund
).
Chapter 7: Dopaminergic Neurotransmission (John A. Schetz and David R.
Sibley).
Chapter 8: Serotonin Systems (John A. Gray and Bryan L. Roth).
Chapter 9: Neuropharmacology of Histamine in Brain (Raphae¿l Faucard and
Jean-Charles Schwartz).
Chapter 10: Ionotropic Glutamate Receptors (David Bleakman, Andrew Alt,
David Lodge, Daniel T. Monaghan, David E. Jane, and Eric S. Nisenbaum).
Chapter 11: Metabotropic Glutamate Receptors (James A. Monn, Michael P.
Johnson, and Darryle D. Schoepp).
Chapter 12: Pharmacology of the GABAA Receptor (Dmytro Berezhnoy, Maria C.
Gravielle, and David H. Farb).
Chapter 13: Metabotropic GABA Receptors (Martin Gassmann and Bernhard
Bettler).
Chapter 14: Voltage-Gated Ion Channels (Alex Fay, Patrick C. G. Haddick,
and Lily Yeh Jan).
Chapter 15: Neuropeptides (Fleur L. Strand).
Chapter 16: Neurotransmitter Transporters (Jia Hu, Katherine Leitzell, Dan
Wang, and Michael W. Quick).
Chapter 17: Gaseous Signaling: Nitric Oxide and Carbon Monoxide as
Messenger Molecules (Kenny K. K. Chung, Valina L. Dawson, and Ted M. Dawson
).
PART II: MOOD DISORDERS.
Chapter 18: Neurobiology and Treatment of Depression (Alexander Neumeister,
Dennis S. Charney, Gerard Sanacora, and John H. Krystal).
Chapter 19: Neurotrophic Factors in Etiology and Treatment of Mood
Disorders (Ronald S. Duman).
Chapter 20: Antidepressant Treatment and Hippocampal Neurogenesis:
Monoamine and Stress Hypotheses of Depression Converge (Alex Dranovsky and
René Hen).
Chapter 21: Neuroendocrine Abnormalities in Women with Depression Linked to
the Reproductive Cycle (Barbara L. Parry, Charles J. Meliska, L. Fernando
Martinez, Eva L. Maurer, Ana M. Lopez, and Diane L. Sorenson).
Chapter 22: Neurobiology and Pharmacotherapy of Bipolar Disorder (R. H.
Belmaker, G. Agam, and R. H. Lenox).
Index.
Cumulative Index.
VOLUME 2.
PART I: ANXIETY AND STRESS DISORDERS.
Chapter 1: Neurobiology of Anxiety (Miklos Toth and Bojana Zupan).
Chapter 2: Pharmacotherapy of Anxiety (Jon R. Nash and David J. Nutt).
Chapter 3: Benzodiazepines (Hartmut Lüddens and Esa R. Korpi).
Chapter 4: Neuroactive Steroids in Anxiety and Stress (Deborah A. Finn and
Robert H. Purdy).
Chapter 5: Emerging Anxiolytics: Corticotropin-Releasing Factor Receptor
Antagonists (Dimitri E. Grigoriadis and Samuel R. J. Hoare).
Chapter 6: Neurobiology and Pharmacotherapy of Obsessive-Compulsive
Disorder (Judith L. Rapoport and Gale Inoff-Germain).
PART II: SCHIZOPHRENIA AND PSYCHOSIS.
Chapter 7: Phenomenology and Clinical Science of Schizophrenia (Subroto
Ghose and Carol Tamminga).
Chapter 8: Dopamine and Glutamate Hypotheses of Schizophrenia (Bita
Moghaddam and Houman Homayoun).
Chapter 9: Molecular Genetics of Schizophrenia (Liam Carroll, Michael C.
O'Donovan, and Michael J. Owen).
Chapter 10: Postmortem Brain Studies: Focus on Susceptibility Genes in
Schizophrenia (Shiny V. Mathew, Shruti N. Mitkus, Barbara K. Lipska, Thomas
M. Hyde, and Joel E. Kleinman).
Chapter 11: Pharmacotherapy of Schizophrenia (Zafar Sharif, Seiya Miyamoto,
and Jeffrey A. Lieberman).
Chapter 12: Atypical Antipsychotic Drugs: Mechanism of Action (Herbert Y.
Meltzer).
PART III: SUBSTANCE ABUSE AND ADDICTIVE DISORDERS.
Chapter 13: Introduction to Addictive Disorders: Implications for
Pharmacotherapies (Mary Jeanne Kreek).
Chapter 14: Dopaminergic and GABAergic Regulation of Alcohol-Motivated
Behaviors: Novel Neuroanatomical Substrates (Harry L. June and William J.
A. Eiler II).
Chapter 15: Nicotine (August R. Buchhalter, Reginald V. Fant, and Jack E.
Henningfield).
Chapter 16: Psychostimulants (Leonard L. Howell and Heather L. Kimmel).
Chapter 17: MDMA and Other "Club Drugs" (M. Isabel Colado, Esther O'Shea,
and A. Richard Green).
Chapter 18: Marijuana: Pharmacology and Interaction with the
Endocannabinoid System (Jenny L. Wiley and Billy R. Martin).
Chapter 19: Opiates and Addiction (Frank J. Vocci).
PART IV: PAIN.
Chapter 20: Neuronal Pathways for Pain Processing (Gavril W. Pasternak and
Yahong Zhang).
Chapter 21: Vanilloid Receptor Pathways (Makoto Tominaga).
Chapter 22: Opioid Receptors (Gavril W. Pasternak).
Chapter 23: Advent of A New Generation of Antimigraine Medications (Ana
Recober and Andrew F. Russo).
Index.
Cumulative Index.
VOLUME 3.
PART I: SLEEP AND AROUSAL.
Chapter 1: Function and Pharmacology of Circadian Clocks (Gabriella B.
Lundkvist and Gene D. Block).
Chapter 2: Melatonin Receptors in Central Nervous System (Margarita L.
Dubocovich).
Chapter 3: Narcolepsy: Neuropharmacological Aspects (Seiji Nishino).
Chapter 4: Hypocretin/Orexin System (J. Gregor Sutcliffe and Luis de Lecea
).
Chapter 5: Prokineticins: New Pair of Regulatory Peptides (Michelle Y.
Cheng and Qun-Yong Zhou).
Chapter 6: Sedatives and Hypnotics (Keith A. Wafford and Paul J. Whiting).
PART II: DEVELOPMENT AND DEVELOPMENTAL DISORDERS.
Chapter 7: Regulation of Adult Neurogenesis (Heather A. Cameron).
Chapter 8: Neurotrophic Factors (Franz F. Hefti and Patricia A. Walicke).
Chapter 9: Neurotrophins and Their Receptors (Mark Bothwell).
Chapter 10: Tourette's Syndrome and Pharmacotherapy (Pieter Joost van
Wattum and James F. Leckman).
Chapter 11: Neuropharmacology of Attention-Deficit/Hyperactivity Disorder (
Paul E. A. Glaser, F. Xavier Castellanos, and Daniel S. Margulies).
Chapter 12: Psychopharmacology of Autism Spectrum Disorders (Adriana Di
Martino, Steven G. Dickstein, Alessandro Zuddas, and F. Xavier Castellanos
).
PART III: NEURODEGENERATIVE AND SEIZURE DISORDERS.
Chapter 13: Stroke: Mechanisms of Excitotoxicity and Approaches for Therapy
(Michael J. O'Neill, David Lodge, and James McCulloch).
Chapter 14: Epilepsy: Mechanisms of Drug Action and Clinical Treatment (
William H. Theodore and Michael A. Rogawski).
Chapter 15: Pharmacotherapy for Traumatic Brain Injury (Donald G. Stein and
Stuart W. Hoffman).
Chapter 16: Dementia and Pharmacotherapy: Memory Drugs (Jerry J. Buccafusco
).
Chapter 17: Pharmacotherapy and Treatment of Parkinson's Disease (Wing Lok
Au and Donald B. Calne).
Chapter 18: Parkinson's Disease: Genetics and Pathogenesis (Claudia M.
Testa).
Chapter 19: Invertebrates as Powerful Genetic Models for Human
Neurodegenerative Diseases (Richard Nass and Charles D. Nichols).
PART IV: NEUROIMMUNOLOGY.
Chapter 20: Myelin Lipids and Proteins: Structure, Function, and Roles in
Neurological Disorders (Richard H. Quarles).
Chapter 21: Pharmacology of Inflammation (Carmen Espejo and Roland Martin
).
Chapter 22: Pharmacological Treatment of Multiple Sclerosis (B. Mark Keegan
).
Chapter 23: Novel Therapies for Multiple Sclerosis (Martin S. Weber and
Scott S. Zamvil).
Chapter 24: Neuropharmacology of HIV/AIDS (Sidney A. Houff and Eugene O.
Major).
PART V: EATING AND METABOLIC DISORDERS.
Chapter 25: Leptin: A Metabolic Perspective (Dawn M. Penn, Cherie R. Rooks,
and Ruth B. S. Harris).
Chapter 26: Ghrelin: Structural and Functional Properties (Birgitte Holst,
Kristoffer Egerod, and Thue W. Schwartz).
Chapter 27: Mechanisms Controlling Adipose Tissue Metabolism by the
Sympathetic Nervous System: Anatomical and Molecular Aspects (Sheila
Collins, Renato H. Migliorini, and Timothy J. Bartness).
Chapter 28: Antiobesity Pharmacotherapy: Current Treatment Options and
Future Perspectives (Yuguang Shi).
Index.
Cumulative Index.

Rezensionen

"...an admirable job of bringing together many aspects of neuropharmacology in one place...well worth your while to examine it." ( Journal of Medicinal Chemistry , September 20, 2007)