Table of contents:
Metal-ligand interactions and metal metabolism; metal ion-ligand interactions and metal toxicity; metal-ligand interactions and free radicals; metal ion-drug interactions; metal complexes as drugs; metal-ligand complexes in diagnosis; chemical speciation and its potential applications to medicine; metal and ligand determinations in biological fluids; experimental speciation of metal ions in biological fluids; applications of computer-aided speciation to bioinorganic medicine.
Detailing the complex chemistry of metal ions, this comprehensive hand book offers easy access to thoroughly up-to-date information on all topics in bioinorganic chemistry. It aims to bridge the gap in understanding between inorganic chemists and the medical profession.;This volume: outlines the physiological effects of specific metal-ligand reactants; reviews the basic thermodynamic theories of metal complex equilibria; discusses metal ion interactions with macromolecules and the main classes of small endogenous ligands; examines metal metabolism, toxicity, and free radical reactivity; considers metal ion interactions with different classes of drugs; covers the potential medical applications of chemical speciation; and furnishes over 6200 bibliographic citations.
Metal-ligand interactions and metal metabolism; metal ion-ligand interactions and metal toxicity; metal-ligand interactions and free radicals; metal ion-drug interactions; metal complexes as drugs; metal-ligand complexes in diagnosis; chemical speciation and its potential applications to medicine; metal and ligand determinations in biological fluids; experimental speciation of metal ions in biological fluids; applications of computer-aided speciation to bioinorganic medicine.
Detailing the complex chemistry of metal ions, this comprehensive hand book offers easy access to thoroughly up-to-date information on all topics in bioinorganic chemistry. It aims to bridge the gap in understanding between inorganic chemists and the medical profession.;This volume: outlines the physiological effects of specific metal-ligand reactants; reviews the basic thermodynamic theories of metal complex equilibria; discusses metal ion interactions with macromolecules and the main classes of small endogenous ligands; examines metal metabolism, toxicity, and free radical reactivity; considers metal ion interactions with different classes of drugs; covers the potential medical applications of chemical speciation; and furnishes over 6200 bibliographic citations.