Handbook of Toxicology of Chemical Warfare Agents

Herausgeber: Gupta, Ramesh C

• Gebundenes Buch

Produktbeschreibung

Provides a comprehensive overview of key topics both on the theoretical side and the experimental Discusses important properties that impact metal oxide performance, processing methods (both novel and accepted), and important applications Reviews the most relevant applications, such as biomedical, energy, electronics and materials applications

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Produktdetails

• Verlag: Elsevier Science
• 3rd edition
• Seitenzahl: 1318
• Erscheinungstermin: 27. April 2020
• Englisch
• Abmessung: 279mm x 221mm x 54mm
• Gewicht: 2912g
• ISBN-13: 9780128190906
• ISBN-10: 0128190906
• Artikelnr.: 58411615

Inhaltsangabe

Section I: Historical Perspective and Epidemiology 1. History of
Toxicology: From Killers to Healers; 2. Historical Perspective of Chemical
Warfare Agents; 3. Global Impact of Chemical Warfare Agents Used Before and
After 1945; 4. Sarin Attacks in Japan: Acute and Delayed Health Effects in
Survivors; 5. Early and Delayed Effects of Sulfur Mustard in Iranian
Veterans After the Iraq-Iran Conflict; 6. Epidemiology of Chemical Warfare
Agents; 7. Chemical Weapons of Mass Destruction and Terrorism: A Threat
Analysis
Section II: Agents That Can Be Used as Weapons of Mass Destruction 8.
Organophosphate Nerve Agents; 9. Russian VX; 10. Novichoks; 11. Blister
Agents; 12. Riot Control Agents; 13. Phosgene oxime; 14. Psychotomimetic
Agent BZ (3-Quinuclidinyl Benzilate); 15. Fluoroacetate; 16. Strychnine;
17. Superwarfarins; 18. PCBs, Dioxins and Furans: Human Exposure and Health
Effects; 19. Polycyclic Aromatic Hydrocarbons: Implications for
Developmental, Molecular, and Behavioral Neurotoxicity; 20. Thallium; 21.
Arsenicals: Toxicity, Their Use as Chemical Warfare Agents, and Possible
Remedial Measures; 22. Chlorine; 23. Phosgene; 24. Carbon Monoxide: Can't
See, Can't Smell, Body Looks Red But They Are Dead; 25. Acute Cyanide
Toxicity and its Treatment: The Body is Dead and Maybe Red but Does Not
Stay Red for Long; 26. Methyl Isocyanate: The Bhopal Gas; 27. Other Toxic
Chemicals as Potential Chemical Warfare Agents; 28. Ricin; 29. Botulinum
Toxin; 30. Onchidal and Fasciculins; 31. Cyanobacterial (Blue-Green Algae)
Toxins
Section III: Target Organ Toxicity 32. Chemical Warfare Agents and the
Nervous System; 33. Behavioral Toxicity of Nerve Agents; 34. The
Respiratory Toxicity of Chemical Warfare Agents; 35. Cardiovascular System
as a Target of Chemical Warfare Agents; 36. Ocular Toxicity of Chemical
Warfare Agents; 37. Skeletal Muscle; 38. Dermal Toxicity of Sulfur Mustard;
39. Reproductive Toxicity and Endocrine Disruption of Potential Chemical
Warfare Agents; 40. Liver Toxicity of Chemical Warfare Agents; 41. Renal
System; 42. Impact of Chemical Warfare Agents on the Immune System
Section IV: Special Topics 43. Health Effects of Nuclear Weapons and
Releases of Radioactive Materials; 44. Clinical and Cellular Aspects of
Traumatic Brain Injury; 45. Neurological Effects and Mechanisms of Blast
Overpressure Injury; 46. Genomics and Proteomics in Brain Complexity in
Relation to Chemically-Induced PTSD; 47. Excitotoxicity, Oxidative Stress,
and Neuronal Injury; 48. Blood-Brain Barrier Damage and Dysfunction by
Chemical Toxicity; 49. The Effects of Organophosphates in the Early Stages
of Human Skeletal Muscle Regeneration; 50. Experimental modeling for
delayed effects of organophosphates; 51. Alternative Animal Toxicity
Testing of Chemical Warfare Agents
Section V: Toxicokinetics, Toxicodynamics and Physiologically-Based
Pharmacokinetics 52. Toxicokinetic Aspects of Nerve Agents and Vesicants;
53. Toxicokinetics and Toxicodynamics of DFP; 54. Physiologically Based
Pharmacokinetic Modeling of Chemical Warfare Agents; 55. Biotransformation
of Warfare Nerve Agents
Section VI: Analytical Methods, Biosensors and Biomarkers 56. Laboratory
Analysis of Chemical Warfare Agents, Adducts, and Metabolites in Biomedical
Samples; 57. On-Site Detection of Chemical Warfare Agents; 58. Neuropathy
Target Esterase as a Biomarker and Biosensor of Delayed Neuropathic Agents;
59. The crosslinking action of organophosphorus poisons; implications for
chronic neurotoxicity; 60. Monitoring of Blood Cholinesterase Activity in
Workers Exposed to Nerve Agents
Section VII: Risks to Animals and Wildlife 61. Potential Agents That Can
Cause Contamination of Animal Feed stuff and Terror; 62. Chemical Warfare
Agents and Risks to Animal Health; 63. Threats to Wildlife by Chemical and
Warfare Agents
Section VIII: Emergency Preparedness, Prophylactic, Therapeutic and
Countermeasures 64. Pharmacological Prophylaxis Against Nerve Agent
Poisoning: Experimental Studies and Practical Implications; 65.
Prophylactic and Therapeutic Measures in Nerve Agents Poisoning; 66.
Physiologically Based Pharmacokinetic/Pharmacodynamic Modeling of
Countermeasures to Nerve Agents; 67. Research on Medical Countermeasures
for Chemical Attacks on Civilians; 68. Pyridinium Oximes in the Treatment
of Poisoning with Organophosphorus Compounds; 69. Novel Cholinesterase
Reactivators; 70. Paraoxonase (PON1), detoxication of nerve agents, and
modulation of their toxicity; 71. The role of carboxylesterases in
therapeutic interventions of nerve agent poisoning; 72. Catalytic
bioscavengers: the new generation of bioscavenger-based medical
countermeasures
Section IX: Decontamination and Detoxification 73. Rapid Decontamination of
Chemical Warfare Agents from the Skin