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Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. Harry B. Demopoulos, MD is an pioneer in the medical aspects of free radicals, especially in the areas of ischaemic injury, the toxicity of anticancer drugs, and in spinal cord injury. He has also been a film actor and is currently a member of the Board of Trustees of the Doris Duke Charitable Foundation. Ischaemic injury is an important cause of morbidity and mortality in humans. For example, most deaths in stroke and heart attack are secondary to ischaemic injury, a consequence of the ischemic cascade.