Head and Neck Cancer
Multimodality Management
Herausgegeben:Bernier, Jacques
Head and Neck Cancer
Multimodality Management
Herausgegeben:Bernier, Jacques
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This second edition provides a comprehensive view of consolidated and innovative concepts, in terms of both diagnosis and treatment. Written by leading international physicians and investigators, this book emphasizes the necessity of combining local and systemic treatments to achieve the objective of yielding higher cure rates and lower toxicities. Heavily updated from the previous edition, it highlights new surgery and radiotherapy techniques, disease awareness, patient quality of life, and comprehensive management. Head-and-neck cancers are a complex clinical entity and their response to…mehr
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This second edition provides a comprehensive view of consolidated and innovative concepts, in terms of both diagnosis and treatment. Written by leading international physicians and investigators, this book emphasizes the necessity of combining local and systemic treatments to achieve the objective of yielding higher cure rates and lower toxicities. Heavily updated from the previous edition, it highlights new surgery and radiotherapy techniques, disease awareness, patient quality of life, and comprehensive management.
Head-and-neck cancers are a complex clinical entity and their response to treatment is also known to vary markedly in function of host-related factors. Notwithstanding the impressive progresses observed in the field of imaging, head and neck cancers are often diagnosed at a late stage and the presence of locally advanced disease in a significant number of patients implies the use of aggressive treatments in order to both ensure local disease control and reduce distant metastasis risks.
In comparison with the first edition, Head and Neck Cancer, Second Edition provides a detailed update of innovative concepts in chemo- and bio-radiation, viral infection impact on tumor growth and response to treatment, and impact of tumor- and host-related factors on treatment outcome.
Head-and-neck cancers are a complex clinical entity and their response to treatment is also known to vary markedly in function of host-related factors. Notwithstanding the impressive progresses observed in the field of imaging, head and neck cancers are often diagnosed at a late stage and the presence of locally advanced disease in a significant number of patients implies the use of aggressive treatments in order to both ensure local disease control and reduce distant metastasis risks.
In comparison with the first edition, Head and Neck Cancer, Second Edition provides a detailed update of innovative concepts in chemo- and bio-radiation, viral infection impact on tumor growth and response to treatment, and impact of tumor- and host-related factors on treatment outcome.
Produktdetails
- Produktdetails
- Verlag: Springer / Springer International Publishing / Springer, Berlin
- Artikelnr. des Verlages: 978-3-319-27599-4
- 1st ed. 2016
- Seitenzahl: 904
- Erscheinungstermin: 1. November 2016
- Englisch
- Abmessung: 285mm x 215mm x 51mm
- Gewicht: 2581g
- ISBN-13: 9783319275994
- ISBN-10: 3319275992
- Artikelnr.: 44048062
- Verlag: Springer / Springer International Publishing / Springer, Berlin
- Artikelnr. des Verlages: 978-3-319-27599-4
- 1st ed. 2016
- Seitenzahl: 904
- Erscheinungstermin: 1. November 2016
- Englisch
- Abmessung: 285mm x 215mm x 51mm
- Gewicht: 2581g
- ISBN-13: 9783319275994
- ISBN-10: 3319275992
- Artikelnr.: 44048062
After obtaining his degree in Radio-Oncology at the University of Liege, Belgium, Jacques Bernier completed his training at the MD Anderson Cancer Center, Houston, and the Curie Institute, Paris. In 2006 he joined the Swiss Genolier Medical Network, where since then he has been chairing the Radio-Oncology Department. Throughout most of his career, Jacques Bernier has been heavily involved with translational and clinical research. From 2000 to 2006 Jacques Bernier was Chairman of the Head and Neck Group of the EORTC. He currently serves as an Editorial Board member of various international peer-reviewed journals, including ¿Journal of Clinical Oncology¿. He is an Associate Editor of ¿Annals of Oncology¿ (since 2010), and ¿Oral Oncology¿ (since January 2011). A Course Director at the European School of Oncology since 1990, Jacques Bernier is also the Chairman of the International Conference on Translational Research in Radio-Oncology - ICTR, organized every three years in Switzerland. He serves as a regular member of advisory boards for many pharmaceutical companies. He is President of the Foundation for the Advancement of Radiation Oncology ¿ FARO, in Geneva, member of the Executive Board of Euro-Asian Society of Mastology - EURAMA, Board of Trustees of ¿Science for Peace¿ and Scientific Committee of the ¿Umberto Veronesi Foundation¿ in Milan.
Table of ContentsHead and Neck Cancer: Multimodality Management, 2nd Edition
Editors: Jacques Bernier
Ch. 1: Epidemiology and Aetiology of Head and Neck CancersNewell W. JohnsonHemantha K. Amarasinghe
Ch. 2: Head and Neck Cancer PreventionFausto ChiesaAngelo OstuniRoberto GrigolatoLuca CalabreseMohssen Ansarin
Ch. 3: Cellular and Molecular Pathology of Head and Neck TumorsAdel K. El-Naggar
Ch. 4: Oncogenomics/Proteomics of Head and Neck CancersJason I. KassHoward S. MoskowitzJennifer R. Grandis
Ch. 5: Genetics and Epigenetics of Head and Neck CancerJagtar DhandaRichard J. Shaw
Ch. 6: Immunology of Head and Neck CancerBenjamin A. KansySteve C. LeeRobert L. Ferris
Ch. 7: Biomarkers in Head and Neck CancerHyunseok KangChristine H. ChungArlene A. Forastiere
Ch. 8: HPV and EBV in Head and Neck CancerJeffrey BrumbaughRobert L. FerrisShen Hu
Ch. 9: Head and Neck Cancer Staging and Prognosis: Perspectives of the UICC and the AJCCBrian O'SullivanJatin P. ShahWilliam M. Lydiatt
Ch. 10: Preclinical Models of Head and Neck Squamous Cell CarcinomaC.L. ZuurA.J.C. DohmenMichiel W. van den BrekelXiao-Jing WangStephen Malkoski
Ch. 11: Translational Research in Head and Neck OncologyDavid S. YooDavid M. Brizel
Ch. 12: Hypoxia in Head and Neck Cancers: Clinical Relevance and TreatmentYungan TaoJean Bourhis
Ch. 13: Imaging of Head and Neck CancersTaha S. MerajSuyash MohanGaurang V. Shah
Ch. 14: Ultrasound Investigations in Head & Neck Cancer PatientsYolanda Y.P. LeeKa Tak WongKunwar Suryaveer Singh BhatiaAnil Tejbhan Ahuja
Ch. 15: Sentinel Node BiopsyOliver J. SmithLee W.T. AlkureishiGary L. Ross
Ch. 16: Intensity-Modulated Radiation Therapy for Head and Neck CancerMarsha ReyngoldEdward J. ShinNancy Lee
Ch. 17: Stereotactic Radiotherapy in Head and Neck Cancer PatientsThomas LeroyEric Lartigau
Ch. 18: Proton Beam Therapy for Head and Neck CancerDanielle N. MargalitJudy A. AdamsHanne M. KooyAnnie W. ChanCh. 20: Molecular Targeted Therapies in Head and Neck CancerZachary S. MorrisAnne M. TraynorPaul M. Harari
Ch. 21: Laser Endoscopic TreatmentPierre MoreauPierre Demez
Ch. 22: Transoral robotic surgery in head and neck cancerSylvain Morinière
Ch. 23: Multidisciplinary Management of Skull Base and Superstructure TumorsGiulio CantùCarlo L. SoleroStefano RiccioSarah ColomboMadia Pompilio
Ch. 24: Multidisciplinary management of oral cavity and maxillary sinus cancersAlexander D. Rapidis
Ch. 25: Oral OncologyRuth Aponte WessonTheresa M. HofstedeRichard C. CardosoPattii MontgomeryAlexander M. WonJack W. MartinMark S. Chambers
Ch. 26: Management of Nasopharyngeal CarcinomaWai Tong NgRoger K.C. NganSiu Hong ChanHenry SzeJimmy Y.W. ChanAnne W.M. Lee
Ch. 27: Multidisciplinary management of oropharynx carcinomasBeth M. BeadleDavid I. Rosenthal
Ch. 28: Multidisciplinary Management of Hypopharyngeal CarcinomaMarc HamoirJean-Pascal MachielsSandra SchmitzVincent Gregoire
Ch. 29: Cancers of the Larynx: Tis, T1, T2 Evaluation and ManagementCarol M. LewisSteven B. ChinnChris HolsingerRandal S. Weber
Ch. 30: Diagnosis and Multidisciplinary Treatment of Laryngeal CancersNabil F. SabaJ. Trad WadsworthJonathan J. BeitlerFadlo R. Khuri
Ch. 31: Programs of Organ and Function PreservationJean Louis Lefebvre
Ch. 32: Principles and New Approaches in Surgical ReconstructionAndreas DietzMilos FischerChristina MagillBruce H. Haughey
Ch. 33: Multidisciplinary treatment of the neckRemco de BreeJohannes A. LangendijkC.R. Leemans
Ch. 34: Postoperative Management of High-Risk Resectable Head and Neck CancerAssuntina G. SaccoEzra E. Cohen
Ch. 35: Multidisciplinary Approach of Unresectable Head and Neck CancerRicardo HittAna Lopez-MartinJuan J. CruzRobert I. Haddad
Ch. 36: Management of Salivary Gland CancerLaura D. LocatiMarco GuzzoEster OrlandiLisa Licitra
Ch. 37: Primary Mucosal Melanomas of the Head and NeckJuliette ThariatAnne-Catherine BaglinPierre Yves MarcyCaroline EvenAntoine Moya-PlanaYusuke DemizuAdam S. GardenMarco KrengliMichael A. Postow
Ch. 38: Head & Neck Cutaneous MelanomaMina N. LeMichael A. PostowSnehal G. Patel
Ch. 39: Cervical Lymph Node Metastases Of Squamous Cell Carcinoma From An Unknown Primary SiteNicholas PavlidisGeorgios Plataniotis
Ch. 40: The Management of Thyroid and Parathyroid CancerNasheed M. HossainColleen VeloskiRanee Mehra
Ch. 41: Head and Neck ParagangliomasJulian KünzelMichael HainzHeidi RossmannChristoph Matthias
Ch. 42: Systemic Treatment of Recurrent/Metastatic Squamous Cell Carcinoma of the Head and NeckPetr SzturzJan B. Vermorken
Ch. 43: Phase I study methodology in head and neck oncologyAaron HansenChristophe Le Tourneau
Ch. 44: Treatment of the Elderly Head and Neck Cancer PatientJean-Claude HoriotMatti Aapro
Ch. 45: Normal Tissue Complications and Protection in Head and Neck Cancer PatientsAndy TrottiNikhil RaoAvraham EisbruchDavid I. Rosenthal
Ch. 46: Advances in Management of Complications for Head and Neck Cancer TherapyBarbara MurphyJie DengMark J. StavasHeidi GanzerJoel B. Epstein
Ch. 47: Rehabilitation of Heavily Treated Head and Neck Cancer PatientsKatherine A. Hutcheson
Ch. 48: Salvage Therapy in Head and Neck Cancer PatientsJohn HeaphyRod RezaeePierre Lavertu
Ch. 49: Quality of Life in Head and Neck Cancer PatientsJolie Ringash
Ch. 50: Psycho-oncologic aspects of head and neck cancer patientsMichel Reich
Ch. 51: Advances in Nanomedicine for Head and Neck CancerSajanlal R. PanikkanvalappilMostafa A. El-SayedIvan H. El-Sayed
Ch. 52: Head and Neck Quality Assurance 2014Thomas J. FitzGeraldMaryann Bishop-JodoinDavid S. FollowillJames M. GalvinMichael V. KnoppJeff M. MichalskiMark RosenJonathan M. GlanzmanPaul RavaAllison SacherDavid J. GoffAlec VaeziKenneth Ulin
Editors: Jacques Bernier
Ch. 1: Epidemiology and Aetiology of Head and Neck CancersNewell W. JohnsonHemantha K. Amarasinghe
Ch. 2: Head and Neck Cancer PreventionFausto ChiesaAngelo OstuniRoberto GrigolatoLuca CalabreseMohssen Ansarin
Ch. 3: Cellular and Molecular Pathology of Head and Neck TumorsAdel K. El-Naggar
Ch. 4: Oncogenomics/Proteomics of Head and Neck CancersJason I. KassHoward S. MoskowitzJennifer R. Grandis
Ch. 5: Genetics and Epigenetics of Head and Neck CancerJagtar DhandaRichard J. Shaw
Ch. 6: Immunology of Head and Neck CancerBenjamin A. KansySteve C. LeeRobert L. Ferris
Ch. 7: Biomarkers in Head and Neck CancerHyunseok KangChristine H. ChungArlene A. Forastiere
Ch. 8: HPV and EBV in Head and Neck CancerJeffrey BrumbaughRobert L. FerrisShen Hu
Ch. 9: Head and Neck Cancer Staging and Prognosis: Perspectives of the UICC and the AJCCBrian O'SullivanJatin P. ShahWilliam M. Lydiatt
Ch. 10: Preclinical Models of Head and Neck Squamous Cell CarcinomaC.L. ZuurA.J.C. DohmenMichiel W. van den BrekelXiao-Jing WangStephen Malkoski
Ch. 11: Translational Research in Head and Neck OncologyDavid S. YooDavid M. Brizel
Ch. 12: Hypoxia in Head and Neck Cancers: Clinical Relevance and TreatmentYungan TaoJean Bourhis
Ch. 13: Imaging of Head and Neck CancersTaha S. MerajSuyash MohanGaurang V. Shah
Ch. 14: Ultrasound Investigations in Head & Neck Cancer PatientsYolanda Y.P. LeeKa Tak WongKunwar Suryaveer Singh BhatiaAnil Tejbhan Ahuja
Ch. 15: Sentinel Node BiopsyOliver J. SmithLee W.T. AlkureishiGary L. Ross
Ch. 16: Intensity-Modulated Radiation Therapy for Head and Neck CancerMarsha ReyngoldEdward J. ShinNancy Lee
Ch. 17: Stereotactic Radiotherapy in Head and Neck Cancer PatientsThomas LeroyEric Lartigau
Ch. 18: Proton Beam Therapy for Head and Neck CancerDanielle N. MargalitJudy A. AdamsHanne M. KooyAnnie W. ChanCh. 20: Molecular Targeted Therapies in Head and Neck CancerZachary S. MorrisAnne M. TraynorPaul M. Harari
Ch. 21: Laser Endoscopic TreatmentPierre MoreauPierre Demez
Ch. 22: Transoral robotic surgery in head and neck cancerSylvain Morinière
Ch. 23: Multidisciplinary Management of Skull Base and Superstructure TumorsGiulio CantùCarlo L. SoleroStefano RiccioSarah ColomboMadia Pompilio
Ch. 24: Multidisciplinary management of oral cavity and maxillary sinus cancersAlexander D. Rapidis
Ch. 25: Oral OncologyRuth Aponte WessonTheresa M. HofstedeRichard C. CardosoPattii MontgomeryAlexander M. WonJack W. MartinMark S. Chambers
Ch. 26: Management of Nasopharyngeal CarcinomaWai Tong NgRoger K.C. NganSiu Hong ChanHenry SzeJimmy Y.W. ChanAnne W.M. Lee
Ch. 27: Multidisciplinary management of oropharynx carcinomasBeth M. BeadleDavid I. Rosenthal
Ch. 28: Multidisciplinary Management of Hypopharyngeal CarcinomaMarc HamoirJean-Pascal MachielsSandra SchmitzVincent Gregoire
Ch. 29: Cancers of the Larynx: Tis, T1, T2 Evaluation and ManagementCarol M. LewisSteven B. ChinnChris HolsingerRandal S. Weber
Ch. 30: Diagnosis and Multidisciplinary Treatment of Laryngeal CancersNabil F. SabaJ. Trad WadsworthJonathan J. BeitlerFadlo R. Khuri
Ch. 31: Programs of Organ and Function PreservationJean Louis Lefebvre
Ch. 32: Principles and New Approaches in Surgical ReconstructionAndreas DietzMilos FischerChristina MagillBruce H. Haughey
Ch. 33: Multidisciplinary treatment of the neckRemco de BreeJohannes A. LangendijkC.R. Leemans
Ch. 34: Postoperative Management of High-Risk Resectable Head and Neck CancerAssuntina G. SaccoEzra E. Cohen
Ch. 35: Multidisciplinary Approach of Unresectable Head and Neck CancerRicardo HittAna Lopez-MartinJuan J. CruzRobert I. Haddad
Ch. 36: Management of Salivary Gland CancerLaura D. LocatiMarco GuzzoEster OrlandiLisa Licitra
Ch. 37: Primary Mucosal Melanomas of the Head and NeckJuliette ThariatAnne-Catherine BaglinPierre Yves MarcyCaroline EvenAntoine Moya-PlanaYusuke DemizuAdam S. GardenMarco KrengliMichael A. Postow
Ch. 38: Head & Neck Cutaneous MelanomaMina N. LeMichael A. PostowSnehal G. Patel
Ch. 39: Cervical Lymph Node Metastases Of Squamous Cell Carcinoma From An Unknown Primary SiteNicholas PavlidisGeorgios Plataniotis
Ch. 40: The Management of Thyroid and Parathyroid CancerNasheed M. HossainColleen VeloskiRanee Mehra
Ch. 41: Head and Neck ParagangliomasJulian KünzelMichael HainzHeidi RossmannChristoph Matthias
Ch. 42: Systemic Treatment of Recurrent/Metastatic Squamous Cell Carcinoma of the Head and NeckPetr SzturzJan B. Vermorken
Ch. 43: Phase I study methodology in head and neck oncologyAaron HansenChristophe Le Tourneau
Ch. 44: Treatment of the Elderly Head and Neck Cancer PatientJean-Claude HoriotMatti Aapro
Ch. 45: Normal Tissue Complications and Protection in Head and Neck Cancer PatientsAndy TrottiNikhil RaoAvraham EisbruchDavid I. Rosenthal
Ch. 46: Advances in Management of Complications for Head and Neck Cancer TherapyBarbara MurphyJie DengMark J. StavasHeidi GanzerJoel B. Epstein
Ch. 47: Rehabilitation of Heavily Treated Head and Neck Cancer PatientsKatherine A. Hutcheson
Ch. 48: Salvage Therapy in Head and Neck Cancer PatientsJohn HeaphyRod RezaeePierre Lavertu
Ch. 49: Quality of Life in Head and Neck Cancer PatientsJolie Ringash
Ch. 50: Psycho-oncologic aspects of head and neck cancer patientsMichel Reich
Ch. 51: Advances in Nanomedicine for Head and Neck CancerSajanlal R. PanikkanvalappilMostafa A. El-SayedIvan H. El-Sayed
Ch. 52: Head and Neck Quality Assurance 2014Thomas J. FitzGeraldMaryann Bishop-JodoinDavid S. FollowillJames M. GalvinMichael V. KnoppJeff M. MichalskiMark RosenJonathan M. GlanzmanPaul RavaAllison SacherDavid J. GoffAlec VaeziKenneth Ulin
Table of Contents Head and Neck Cancer: Multimodality Management, 2nd Edition
Editors: Jacques Bernier
Ch. 1: Epidemiology and Aetiology of Head and Neck Cancers Newell W. Johnson Hemantha K. Amarasinghe
Ch. 2: Head and Neck Cancer Prevention Fausto Chiesa Angelo Ostuni Roberto Grigolato Luca Calabrese Mohssen Ansarin
Ch. 3: Cellular and Molecular Pathology of Head and Neck Tumors Adel K. El-Naggar
Ch. 4: Oncogenomics/Proteomics of Head and Neck Cancers Jason I. Kass Howard S. Moskowitz Jennifer R. Grandis
Ch. 5: Genetics and Epigenetics of Head and Neck Cancer Jagtar Dhanda Richard J. Shaw
Ch. 6: Immunology of Head and Neck Cancer Benjamin A. Kansy Steve C. Lee Robert L. Ferris
Ch. 7: Biomarkers in Head and Neck Cancer Hyunseok Kang Christine H. Chung Arlene A. Forastiere
Ch. 8: HPV and EBV in Head and Neck Cancer Jeffrey Brumbaugh Robert L. Ferris Shen Hu
Ch. 9: Head and Neck Cancer Staging and Prognosis: Perspectives of the UICC and the AJCC Brian O’Sullivan Jatin P. Shah William M. Lydiatt
Ch. 10: Preclinical Models of Head and Neck Squamous Cell Carcinoma C.L. Zuur A.J.C. Dohmen Michiel W. van den Brekel Xiao-Jing Wang Stephen Malkoski
Ch. 11: Translational Research in Head and Neck Oncology David S. Yoo David M. Brizel
Ch. 12: Hypoxia in Head and Neck Cancers: Clinical Relevance and Treatment Yungan Tao Jean Bourhis
Ch. 13: Imaging of Head and Neck Cancers Taha S. Meraj Suyash Mohan Gaurang V. Shah
Ch. 14: Ultrasound Investigations in Head & Neck Cancer Patients Yolanda Y.P. Lee Ka Tak Wong Kunwar Suryaveer Singh Bhatia Anil Tejbhan Ahuja
Ch. 15: Sentinel Node Biopsy Oliver J. Smith Lee W.T. Alkureishi Gary L. Ross
Ch. 16: Intensity-Modulated Radiation Therapy for Head and Neck Cancer Marsha Reyngold Edward J. Shin Nancy Lee
Ch. 17: Stereotactic Radiotherapy in Head and Neck Cancer Patients Thomas Leroy Eric Lartigau
Ch. 18: Proton Beam Therapy for Head and Neck Cancer Danielle N. Margalit Judy A. Adams Hanne M. Kooy Annie W. Chan < Ch. 19: Principles of Systemic Chemotherapy for Squamous Cell Head and Neck Cancer Cristina P. Rodriguez David J. Adelstein
Ch. 20: Molecular Targeted Therapies in Head and Neck Cancer Zachary S. Morris Anne M. Traynor Paul M. Harari
Ch. 21: Laser Endoscopic Treatment Pierre Moreau Pierre Demez
Ch. 22: Transoral robotic surgery in head and neck cancer Sylvain Morinière
Ch. 23: Multidisciplinary Management of Skull Base and Superstructure Tumors Giulio Cantù Carlo L. Solero Stefano Riccio Sarah Colombo Madia Pompilio
Ch. 24: Multidisciplinary management of oral cavity and maxillary sinus cancers Alexander D. Rapidis
Ch. 25: Oral Oncology Ruth Aponte Wesson Theresa M. Hofstede Richard C. Cardoso Pattii Montgomery Alexander M. Won Jack W. Martin Mark S. Chambers
Ch. 26: Management of Nasopharyngeal Carcinoma Wai Tong Ng Roger K.C. Ngan Siu Hong Chan Henry Sze Jimmy Y.W. Chan Anne W.M. Lee
Ch. 27: Multidisciplinary management of oropharynx carcinomas Beth M. Beadle David I. Rosenthal
Ch. 28: Multidisciplinary Management of Hypopharyngeal Carcinoma Marc Hamoir Jean-Pascal Machiels Sandra Schmitz Vincent Gregoire
Ch. 29: Cancers of the Larynx: Tis, T1, T2 Evaluation and Management Carol M. Lewis Steven B. Chinn Chris Holsinger Randal S. Weber
Ch. 30: Diagnosis and Multidisciplinary Treatment of Laryngeal Cancers Nabil F. Saba J. Trad Wadsworth Jonathan J. Beitler Fadlo R. Khuri
Ch. 31: Programs of Organ and Function Preservation Jean Louis Lefebvre
Ch. 32: Principles and New Approaches in Surgical Reconstruction Andreas Dietz Milos Fischer Christina Magill Bruce H. Haughey
Ch. 33: Multidisciplinary treatment of the neck Remco de Bree Johannes A. Langendijk C.R. Leemans
Ch. 34: Postoperative Management of High-Risk Resectable Head and Neck Cancer Assuntina G. Sacco Ezra E. Cohen
Ch. 35: Multidisciplinary Approach of Unresectable Head and Neck Cancer Ricardo Hitt Ana Lopez-Martin Juan J. Cruz Robert I. Haddad
Ch. 36: Management of Salivary Gland Cancer Laura D. Locati Marco Guzzo Ester Orlandi Lisa Licitra
Ch. 37: Primary Mucosal Melanomas of the Head and Neck Juliette Thariat Anne-Catherine Baglin Pierre Yves Marcy Caroline Even Antoine Moya-Plana Yusuke Demizu Adam S. Garden Marco Krengli Michael A. Postow
Ch. 38: Head & Neck Cutaneous Melanoma Mina N. Le Michael A. Postow Snehal G. Patel
Ch. 39: Cervical Lymph Node Metastases Of Squamous Cell Carcinoma From An Unknown Primary Site Nicholas Pavlidis Georgios Plataniotis
Ch. 40: The Management of Thyroid and Parathyroid Cancer Nasheed M. Hossain Colleen Veloski Ranee Mehra
Ch. 41: Head and Neck Paragangliomas Julian Künzel Michael Hainz Heidi Rossmann Christoph Matthias
Ch. 42: Systemic Treatment of Recurrent/Metastatic Squamous Cell Carcinoma of the Head and Neck Petr Szturz Jan B. Vermorken
Ch. 43: Phase I study methodology in head and neck oncology Aaron Hansen Christophe Le Tourneau
Ch. 44: Treatment of the Elderly Head and Neck Cancer Patient Jean-Claude Horiot Matti Aapro
Ch. 45: Normal Tissue Complications and Protection in Head and Neck Cancer Patients Andy Trotti Nikhil Rao Avraham Eisbruch David I. Rosenthal
Ch. 46: Advances in Management of Complications for Head and Neck Cancer Therapy Barbara Murphy Jie Deng Mark J. Stavas Heidi Ganzer Joel B. Epstein
Ch. 47: Rehabilitation of Heavily Treated Head and Neck Cancer Patients Katherine A. Hutcheson
Ch. 48: Salvage Therapy in Head and Neck Cancer Patients John Heaphy Rod Rezaee Pierre Lavertu
Ch. 49: Quality of Life in Head and Neck Cancer Patients Jolie Ringash
Ch. 50: Psycho-oncologic aspects of head and neck cancer patients Michel Reich
Ch. 51: Advances in Nanomedicine for Head and Neck Cancer Sajanlal R. Panikkanvalappil Mostafa A. El-Sayed Ivan H. El-Sayed
Ch. 52: Head and Neck Quality Assurance 2014 Thomas J. FitzGerald Maryann Bishop-Jodoin David S. Followill James M. Galvin Michael V. Knopp Jeff M. Michalski Mark Rosen Jonathan M. Glanzman Paul Rava Allison Sacher David J. Goff Alec Vaezi Kenneth Ulin
Editors: Jacques Bernier
Ch. 1: Epidemiology and Aetiology of Head and Neck Cancers Newell W. Johnson Hemantha K. Amarasinghe
Ch. 2: Head and Neck Cancer Prevention Fausto Chiesa Angelo Ostuni Roberto Grigolato Luca Calabrese Mohssen Ansarin
Ch. 3: Cellular and Molecular Pathology of Head and Neck Tumors Adel K. El-Naggar
Ch. 4: Oncogenomics/Proteomics of Head and Neck Cancers Jason I. Kass Howard S. Moskowitz Jennifer R. Grandis
Ch. 5: Genetics and Epigenetics of Head and Neck Cancer Jagtar Dhanda Richard J. Shaw
Ch. 6: Immunology of Head and Neck Cancer Benjamin A. Kansy Steve C. Lee Robert L. Ferris
Ch. 7: Biomarkers in Head and Neck Cancer Hyunseok Kang Christine H. Chung Arlene A. Forastiere
Ch. 8: HPV and EBV in Head and Neck Cancer Jeffrey Brumbaugh Robert L. Ferris Shen Hu
Ch. 9: Head and Neck Cancer Staging and Prognosis: Perspectives of the UICC and the AJCC Brian O’Sullivan Jatin P. Shah William M. Lydiatt
Ch. 10: Preclinical Models of Head and Neck Squamous Cell Carcinoma C.L. Zuur A.J.C. Dohmen Michiel W. van den Brekel Xiao-Jing Wang Stephen Malkoski
Ch. 11: Translational Research in Head and Neck Oncology David S. Yoo David M. Brizel
Ch. 12: Hypoxia in Head and Neck Cancers: Clinical Relevance and Treatment Yungan Tao Jean Bourhis
Ch. 13: Imaging of Head and Neck Cancers Taha S. Meraj Suyash Mohan Gaurang V. Shah
Ch. 14: Ultrasound Investigations in Head & Neck Cancer Patients Yolanda Y.P. Lee Ka Tak Wong Kunwar Suryaveer Singh Bhatia Anil Tejbhan Ahuja
Ch. 15: Sentinel Node Biopsy Oliver J. Smith Lee W.T. Alkureishi Gary L. Ross
Ch. 16: Intensity-Modulated Radiation Therapy for Head and Neck Cancer Marsha Reyngold Edward J. Shin Nancy Lee
Ch. 17: Stereotactic Radiotherapy in Head and Neck Cancer Patients Thomas Leroy Eric Lartigau
Ch. 18: Proton Beam Therapy for Head and Neck Cancer Danielle N. Margalit Judy A. Adams Hanne M. Kooy Annie W. Chan < Ch. 19: Principles of Systemic Chemotherapy for Squamous Cell Head and Neck Cancer Cristina P. Rodriguez David J. Adelstein
Ch. 20: Molecular Targeted Therapies in Head and Neck Cancer Zachary S. Morris Anne M. Traynor Paul M. Harari
Ch. 21: Laser Endoscopic Treatment Pierre Moreau Pierre Demez
Ch. 22: Transoral robotic surgery in head and neck cancer Sylvain Morinière
Ch. 23: Multidisciplinary Management of Skull Base and Superstructure Tumors Giulio Cantù Carlo L. Solero Stefano Riccio Sarah Colombo Madia Pompilio
Ch. 24: Multidisciplinary management of oral cavity and maxillary sinus cancers Alexander D. Rapidis
Ch. 25: Oral Oncology Ruth Aponte Wesson Theresa M. Hofstede Richard C. Cardoso Pattii Montgomery Alexander M. Won Jack W. Martin Mark S. Chambers
Ch. 26: Management of Nasopharyngeal Carcinoma Wai Tong Ng Roger K.C. Ngan Siu Hong Chan Henry Sze Jimmy Y.W. Chan Anne W.M. Lee
Ch. 27: Multidisciplinary management of oropharynx carcinomas Beth M. Beadle David I. Rosenthal
Ch. 28: Multidisciplinary Management of Hypopharyngeal Carcinoma Marc Hamoir Jean-Pascal Machiels Sandra Schmitz Vincent Gregoire
Ch. 29: Cancers of the Larynx: Tis, T1, T2 Evaluation and Management Carol M. Lewis Steven B. Chinn Chris Holsinger Randal S. Weber
Ch. 30: Diagnosis and Multidisciplinary Treatment of Laryngeal Cancers Nabil F. Saba J. Trad Wadsworth Jonathan J. Beitler Fadlo R. Khuri
Ch. 31: Programs of Organ and Function Preservation Jean Louis Lefebvre
Ch. 32: Principles and New Approaches in Surgical Reconstruction Andreas Dietz Milos Fischer Christina Magill Bruce H. Haughey
Ch. 33: Multidisciplinary treatment of the neck Remco de Bree Johannes A. Langendijk C.R. Leemans
Ch. 34: Postoperative Management of High-Risk Resectable Head and Neck Cancer Assuntina G. Sacco Ezra E. Cohen
Ch. 35: Multidisciplinary Approach of Unresectable Head and Neck Cancer Ricardo Hitt Ana Lopez-Martin Juan J. Cruz Robert I. Haddad
Ch. 36: Management of Salivary Gland Cancer Laura D. Locati Marco Guzzo Ester Orlandi Lisa Licitra
Ch. 37: Primary Mucosal Melanomas of the Head and Neck Juliette Thariat Anne-Catherine Baglin Pierre Yves Marcy Caroline Even Antoine Moya-Plana Yusuke Demizu Adam S. Garden Marco Krengli Michael A. Postow
Ch. 38: Head & Neck Cutaneous Melanoma Mina N. Le Michael A. Postow Snehal G. Patel
Ch. 39: Cervical Lymph Node Metastases Of Squamous Cell Carcinoma From An Unknown Primary Site Nicholas Pavlidis Georgios Plataniotis
Ch. 40: The Management of Thyroid and Parathyroid Cancer Nasheed M. Hossain Colleen Veloski Ranee Mehra
Ch. 41: Head and Neck Paragangliomas Julian Künzel Michael Hainz Heidi Rossmann Christoph Matthias
Ch. 42: Systemic Treatment of Recurrent/Metastatic Squamous Cell Carcinoma of the Head and Neck Petr Szturz Jan B. Vermorken
Ch. 43: Phase I study methodology in head and neck oncology Aaron Hansen Christophe Le Tourneau
Ch. 44: Treatment of the Elderly Head and Neck Cancer Patient Jean-Claude Horiot Matti Aapro
Ch. 45: Normal Tissue Complications and Protection in Head and Neck Cancer Patients Andy Trotti Nikhil Rao Avraham Eisbruch David I. Rosenthal
Ch. 46: Advances in Management of Complications for Head and Neck Cancer Therapy Barbara Murphy Jie Deng Mark J. Stavas Heidi Ganzer Joel B. Epstein
Ch. 47: Rehabilitation of Heavily Treated Head and Neck Cancer Patients Katherine A. Hutcheson
Ch. 48: Salvage Therapy in Head and Neck Cancer Patients John Heaphy Rod Rezaee Pierre Lavertu
Ch. 49: Quality of Life in Head and Neck Cancer Patients Jolie Ringash
Ch. 50: Psycho-oncologic aspects of head and neck cancer patients Michel Reich
Ch. 51: Advances in Nanomedicine for Head and Neck Cancer Sajanlal R. Panikkanvalappil Mostafa A. El-Sayed Ivan H. El-Sayed
Ch. 52: Head and Neck Quality Assurance 2014 Thomas J. FitzGerald Maryann Bishop-Jodoin David S. Followill James M. Galvin Michael V. Knopp Jeff M. Michalski Mark Rosen Jonathan M. Glanzman Paul Rava Allison Sacher David J. Goff Alec Vaezi Kenneth Ulin
Table of ContentsHead and Neck Cancer: Multimodality Management, 2nd Edition
Editors: Jacques Bernier
Ch. 1: Epidemiology and Aetiology of Head and Neck CancersNewell W. JohnsonHemantha K. Amarasinghe
Ch. 2: Head and Neck Cancer PreventionFausto ChiesaAngelo OstuniRoberto GrigolatoLuca CalabreseMohssen Ansarin
Ch. 3: Cellular and Molecular Pathology of Head and Neck TumorsAdel K. El-Naggar
Ch. 4: Oncogenomics/Proteomics of Head and Neck CancersJason I. KassHoward S. MoskowitzJennifer R. Grandis
Ch. 5: Genetics and Epigenetics of Head and Neck CancerJagtar DhandaRichard J. Shaw
Ch. 6: Immunology of Head and Neck CancerBenjamin A. KansySteve C. LeeRobert L. Ferris
Ch. 7: Biomarkers in Head and Neck CancerHyunseok KangChristine H. ChungArlene A. Forastiere
Ch. 8: HPV and EBV in Head and Neck CancerJeffrey BrumbaughRobert L. FerrisShen Hu
Ch. 9: Head and Neck Cancer Staging and Prognosis: Perspectives of the UICC and the AJCCBrian O'SullivanJatin P. ShahWilliam M. Lydiatt
Ch. 10: Preclinical Models of Head and Neck Squamous Cell CarcinomaC.L. ZuurA.J.C. DohmenMichiel W. van den BrekelXiao-Jing WangStephen Malkoski
Ch. 11: Translational Research in Head and Neck OncologyDavid S. YooDavid M. Brizel
Ch. 12: Hypoxia in Head and Neck Cancers: Clinical Relevance and TreatmentYungan TaoJean Bourhis
Ch. 13: Imaging of Head and Neck CancersTaha S. MerajSuyash MohanGaurang V. Shah
Ch. 14: Ultrasound Investigations in Head & Neck Cancer PatientsYolanda Y.P. LeeKa Tak WongKunwar Suryaveer Singh BhatiaAnil Tejbhan Ahuja
Ch. 15: Sentinel Node BiopsyOliver J. SmithLee W.T. AlkureishiGary L. Ross
Ch. 16: Intensity-Modulated Radiation Therapy for Head and Neck CancerMarsha ReyngoldEdward J. ShinNancy Lee
Ch. 17: Stereotactic Radiotherapy in Head and Neck Cancer PatientsThomas LeroyEric Lartigau
Ch. 18: Proton Beam Therapy for Head and Neck CancerDanielle N. MargalitJudy A. AdamsHanne M. KooyAnnie W. ChanCh. 20: Molecular Targeted Therapies in Head and Neck CancerZachary S. MorrisAnne M. TraynorPaul M. Harari
Ch. 21: Laser Endoscopic TreatmentPierre MoreauPierre Demez
Ch. 22: Transoral robotic surgery in head and neck cancerSylvain Morinière
Ch. 23: Multidisciplinary Management of Skull Base and Superstructure TumorsGiulio CantùCarlo L. SoleroStefano RiccioSarah ColomboMadia Pompilio
Ch. 24: Multidisciplinary management of oral cavity and maxillary sinus cancersAlexander D. Rapidis
Ch. 25: Oral OncologyRuth Aponte WessonTheresa M. HofstedeRichard C. CardosoPattii MontgomeryAlexander M. WonJack W. MartinMark S. Chambers
Ch. 26: Management of Nasopharyngeal CarcinomaWai Tong NgRoger K.C. NganSiu Hong ChanHenry SzeJimmy Y.W. ChanAnne W.M. Lee
Ch. 27: Multidisciplinary management of oropharynx carcinomasBeth M. BeadleDavid I. Rosenthal
Ch. 28: Multidisciplinary Management of Hypopharyngeal CarcinomaMarc HamoirJean-Pascal MachielsSandra SchmitzVincent Gregoire
Ch. 29: Cancers of the Larynx: Tis, T1, T2 Evaluation and ManagementCarol M. LewisSteven B. ChinnChris HolsingerRandal S. Weber
Ch. 30: Diagnosis and Multidisciplinary Treatment of Laryngeal CancersNabil F. SabaJ. Trad WadsworthJonathan J. BeitlerFadlo R. Khuri
Ch. 31: Programs of Organ and Function PreservationJean Louis Lefebvre
Ch. 32: Principles and New Approaches in Surgical ReconstructionAndreas DietzMilos FischerChristina MagillBruce H. Haughey
Ch. 33: Multidisciplinary treatment of the neckRemco de BreeJohannes A. LangendijkC.R. Leemans
Ch. 34: Postoperative Management of High-Risk Resectable Head and Neck CancerAssuntina G. SaccoEzra E. Cohen
Ch. 35: Multidisciplinary Approach of Unresectable Head and Neck CancerRicardo HittAna Lopez-MartinJuan J. CruzRobert I. Haddad
Ch. 36: Management of Salivary Gland CancerLaura D. LocatiMarco GuzzoEster OrlandiLisa Licitra
Ch. 37: Primary Mucosal Melanomas of the Head and NeckJuliette ThariatAnne-Catherine BaglinPierre Yves MarcyCaroline EvenAntoine Moya-PlanaYusuke DemizuAdam S. GardenMarco KrengliMichael A. Postow
Ch. 38: Head & Neck Cutaneous MelanomaMina N. LeMichael A. PostowSnehal G. Patel
Ch. 39: Cervical Lymph Node Metastases Of Squamous Cell Carcinoma From An Unknown Primary SiteNicholas PavlidisGeorgios Plataniotis
Ch. 40: The Management of Thyroid and Parathyroid CancerNasheed M. HossainColleen VeloskiRanee Mehra
Ch. 41: Head and Neck ParagangliomasJulian KünzelMichael HainzHeidi RossmannChristoph Matthias
Ch. 42: Systemic Treatment of Recurrent/Metastatic Squamous Cell Carcinoma of the Head and NeckPetr SzturzJan B. Vermorken
Ch. 43: Phase I study methodology in head and neck oncologyAaron HansenChristophe Le Tourneau
Ch. 44: Treatment of the Elderly Head and Neck Cancer PatientJean-Claude HoriotMatti Aapro
Ch. 45: Normal Tissue Complications and Protection in Head and Neck Cancer PatientsAndy TrottiNikhil RaoAvraham EisbruchDavid I. Rosenthal
Ch. 46: Advances in Management of Complications for Head and Neck Cancer TherapyBarbara MurphyJie DengMark J. StavasHeidi GanzerJoel B. Epstein
Ch. 47: Rehabilitation of Heavily Treated Head and Neck Cancer PatientsKatherine A. Hutcheson
Ch. 48: Salvage Therapy in Head and Neck Cancer PatientsJohn HeaphyRod RezaeePierre Lavertu
Ch. 49: Quality of Life in Head and Neck Cancer PatientsJolie Ringash
Ch. 50: Psycho-oncologic aspects of head and neck cancer patientsMichel Reich
Ch. 51: Advances in Nanomedicine for Head and Neck CancerSajanlal R. PanikkanvalappilMostafa A. El-SayedIvan H. El-Sayed
Ch. 52: Head and Neck Quality Assurance 2014Thomas J. FitzGeraldMaryann Bishop-JodoinDavid S. FollowillJames M. GalvinMichael V. KnoppJeff M. MichalskiMark RosenJonathan M. GlanzmanPaul RavaAllison SacherDavid J. GoffAlec VaeziKenneth Ulin
Editors: Jacques Bernier
Ch. 1: Epidemiology and Aetiology of Head and Neck CancersNewell W. JohnsonHemantha K. Amarasinghe
Ch. 2: Head and Neck Cancer PreventionFausto ChiesaAngelo OstuniRoberto GrigolatoLuca CalabreseMohssen Ansarin
Ch. 3: Cellular and Molecular Pathology of Head and Neck TumorsAdel K. El-Naggar
Ch. 4: Oncogenomics/Proteomics of Head and Neck CancersJason I. KassHoward S. MoskowitzJennifer R. Grandis
Ch. 5: Genetics and Epigenetics of Head and Neck CancerJagtar DhandaRichard J. Shaw
Ch. 6: Immunology of Head and Neck CancerBenjamin A. KansySteve C. LeeRobert L. Ferris
Ch. 7: Biomarkers in Head and Neck CancerHyunseok KangChristine H. ChungArlene A. Forastiere
Ch. 8: HPV and EBV in Head and Neck CancerJeffrey BrumbaughRobert L. FerrisShen Hu
Ch. 9: Head and Neck Cancer Staging and Prognosis: Perspectives of the UICC and the AJCCBrian O'SullivanJatin P. ShahWilliam M. Lydiatt
Ch. 10: Preclinical Models of Head and Neck Squamous Cell CarcinomaC.L. ZuurA.J.C. DohmenMichiel W. van den BrekelXiao-Jing WangStephen Malkoski
Ch. 11: Translational Research in Head and Neck OncologyDavid S. YooDavid M. Brizel
Ch. 12: Hypoxia in Head and Neck Cancers: Clinical Relevance and TreatmentYungan TaoJean Bourhis
Ch. 13: Imaging of Head and Neck CancersTaha S. MerajSuyash MohanGaurang V. Shah
Ch. 14: Ultrasound Investigations in Head & Neck Cancer PatientsYolanda Y.P. LeeKa Tak WongKunwar Suryaveer Singh BhatiaAnil Tejbhan Ahuja
Ch. 15: Sentinel Node BiopsyOliver J. SmithLee W.T. AlkureishiGary L. Ross
Ch. 16: Intensity-Modulated Radiation Therapy for Head and Neck CancerMarsha ReyngoldEdward J. ShinNancy Lee
Ch. 17: Stereotactic Radiotherapy in Head and Neck Cancer PatientsThomas LeroyEric Lartigau
Ch. 18: Proton Beam Therapy for Head and Neck CancerDanielle N. MargalitJudy A. AdamsHanne M. KooyAnnie W. ChanCh. 20: Molecular Targeted Therapies in Head and Neck CancerZachary S. MorrisAnne M. TraynorPaul M. Harari
Ch. 21: Laser Endoscopic TreatmentPierre MoreauPierre Demez
Ch. 22: Transoral robotic surgery in head and neck cancerSylvain Morinière
Ch. 23: Multidisciplinary Management of Skull Base and Superstructure TumorsGiulio CantùCarlo L. SoleroStefano RiccioSarah ColomboMadia Pompilio
Ch. 24: Multidisciplinary management of oral cavity and maxillary sinus cancersAlexander D. Rapidis
Ch. 25: Oral OncologyRuth Aponte WessonTheresa M. HofstedeRichard C. CardosoPattii MontgomeryAlexander M. WonJack W. MartinMark S. Chambers
Ch. 26: Management of Nasopharyngeal CarcinomaWai Tong NgRoger K.C. NganSiu Hong ChanHenry SzeJimmy Y.W. ChanAnne W.M. Lee
Ch. 27: Multidisciplinary management of oropharynx carcinomasBeth M. BeadleDavid I. Rosenthal
Ch. 28: Multidisciplinary Management of Hypopharyngeal CarcinomaMarc HamoirJean-Pascal MachielsSandra SchmitzVincent Gregoire
Ch. 29: Cancers of the Larynx: Tis, T1, T2 Evaluation and ManagementCarol M. LewisSteven B. ChinnChris HolsingerRandal S. Weber
Ch. 30: Diagnosis and Multidisciplinary Treatment of Laryngeal CancersNabil F. SabaJ. Trad WadsworthJonathan J. BeitlerFadlo R. Khuri
Ch. 31: Programs of Organ and Function PreservationJean Louis Lefebvre
Ch. 32: Principles and New Approaches in Surgical ReconstructionAndreas DietzMilos FischerChristina MagillBruce H. Haughey
Ch. 33: Multidisciplinary treatment of the neckRemco de BreeJohannes A. LangendijkC.R. Leemans
Ch. 34: Postoperative Management of High-Risk Resectable Head and Neck CancerAssuntina G. SaccoEzra E. Cohen
Ch. 35: Multidisciplinary Approach of Unresectable Head and Neck CancerRicardo HittAna Lopez-MartinJuan J. CruzRobert I. Haddad
Ch. 36: Management of Salivary Gland CancerLaura D. LocatiMarco GuzzoEster OrlandiLisa Licitra
Ch. 37: Primary Mucosal Melanomas of the Head and NeckJuliette ThariatAnne-Catherine BaglinPierre Yves MarcyCaroline EvenAntoine Moya-PlanaYusuke DemizuAdam S. GardenMarco KrengliMichael A. Postow
Ch. 38: Head & Neck Cutaneous MelanomaMina N. LeMichael A. PostowSnehal G. Patel
Ch. 39: Cervical Lymph Node Metastases Of Squamous Cell Carcinoma From An Unknown Primary SiteNicholas PavlidisGeorgios Plataniotis
Ch. 40: The Management of Thyroid and Parathyroid CancerNasheed M. HossainColleen VeloskiRanee Mehra
Ch. 41: Head and Neck ParagangliomasJulian KünzelMichael HainzHeidi RossmannChristoph Matthias
Ch. 42: Systemic Treatment of Recurrent/Metastatic Squamous Cell Carcinoma of the Head and NeckPetr SzturzJan B. Vermorken
Ch. 43: Phase I study methodology in head and neck oncologyAaron HansenChristophe Le Tourneau
Ch. 44: Treatment of the Elderly Head and Neck Cancer PatientJean-Claude HoriotMatti Aapro
Ch. 45: Normal Tissue Complications and Protection in Head and Neck Cancer PatientsAndy TrottiNikhil RaoAvraham EisbruchDavid I. Rosenthal
Ch. 46: Advances in Management of Complications for Head and Neck Cancer TherapyBarbara MurphyJie DengMark J. StavasHeidi GanzerJoel B. Epstein
Ch. 47: Rehabilitation of Heavily Treated Head and Neck Cancer PatientsKatherine A. Hutcheson
Ch. 48: Salvage Therapy in Head and Neck Cancer PatientsJohn HeaphyRod RezaeePierre Lavertu
Ch. 49: Quality of Life in Head and Neck Cancer PatientsJolie Ringash
Ch. 50: Psycho-oncologic aspects of head and neck cancer patientsMichel Reich
Ch. 51: Advances in Nanomedicine for Head and Neck CancerSajanlal R. PanikkanvalappilMostafa A. El-SayedIvan H. El-Sayed
Ch. 52: Head and Neck Quality Assurance 2014Thomas J. FitzGeraldMaryann Bishop-JodoinDavid S. FollowillJames M. GalvinMichael V. KnoppJeff M. MichalskiMark RosenJonathan M. GlanzmanPaul RavaAllison SacherDavid J. GoffAlec VaeziKenneth Ulin
Table of Contents Head and Neck Cancer: Multimodality Management, 2nd Edition
Editors: Jacques Bernier
Ch. 1: Epidemiology and Aetiology of Head and Neck Cancers Newell W. Johnson Hemantha K. Amarasinghe
Ch. 2: Head and Neck Cancer Prevention Fausto Chiesa Angelo Ostuni Roberto Grigolato Luca Calabrese Mohssen Ansarin
Ch. 3: Cellular and Molecular Pathology of Head and Neck Tumors Adel K. El-Naggar
Ch. 4: Oncogenomics/Proteomics of Head and Neck Cancers Jason I. Kass Howard S. Moskowitz Jennifer R. Grandis
Ch. 5: Genetics and Epigenetics of Head and Neck Cancer Jagtar Dhanda Richard J. Shaw
Ch. 6: Immunology of Head and Neck Cancer Benjamin A. Kansy Steve C. Lee Robert L. Ferris
Ch. 7: Biomarkers in Head and Neck Cancer Hyunseok Kang Christine H. Chung Arlene A. Forastiere
Ch. 8: HPV and EBV in Head and Neck Cancer Jeffrey Brumbaugh Robert L. Ferris Shen Hu
Ch. 9: Head and Neck Cancer Staging and Prognosis: Perspectives of the UICC and the AJCC Brian O’Sullivan Jatin P. Shah William M. Lydiatt
Ch. 10: Preclinical Models of Head and Neck Squamous Cell Carcinoma C.L. Zuur A.J.C. Dohmen Michiel W. van den Brekel Xiao-Jing Wang Stephen Malkoski
Ch. 11: Translational Research in Head and Neck Oncology David S. Yoo David M. Brizel
Ch. 12: Hypoxia in Head and Neck Cancers: Clinical Relevance and Treatment Yungan Tao Jean Bourhis
Ch. 13: Imaging of Head and Neck Cancers Taha S. Meraj Suyash Mohan Gaurang V. Shah
Ch. 14: Ultrasound Investigations in Head & Neck Cancer Patients Yolanda Y.P. Lee Ka Tak Wong Kunwar Suryaveer Singh Bhatia Anil Tejbhan Ahuja
Ch. 15: Sentinel Node Biopsy Oliver J. Smith Lee W.T. Alkureishi Gary L. Ross
Ch. 16: Intensity-Modulated Radiation Therapy for Head and Neck Cancer Marsha Reyngold Edward J. Shin Nancy Lee
Ch. 17: Stereotactic Radiotherapy in Head and Neck Cancer Patients Thomas Leroy Eric Lartigau
Ch. 18: Proton Beam Therapy for Head and Neck Cancer Danielle N. Margalit Judy A. Adams Hanne M. Kooy Annie W. Chan < Ch. 19: Principles of Systemic Chemotherapy for Squamous Cell Head and Neck Cancer Cristina P. Rodriguez David J. Adelstein
Ch. 20: Molecular Targeted Therapies in Head and Neck Cancer Zachary S. Morris Anne M. Traynor Paul M. Harari
Ch. 21: Laser Endoscopic Treatment Pierre Moreau Pierre Demez
Ch. 22: Transoral robotic surgery in head and neck cancer Sylvain Morinière
Ch. 23: Multidisciplinary Management of Skull Base and Superstructure Tumors Giulio Cantù Carlo L. Solero Stefano Riccio Sarah Colombo Madia Pompilio
Ch. 24: Multidisciplinary management of oral cavity and maxillary sinus cancers Alexander D. Rapidis
Ch. 25: Oral Oncology Ruth Aponte Wesson Theresa M. Hofstede Richard C. Cardoso Pattii Montgomery Alexander M. Won Jack W. Martin Mark S. Chambers
Ch. 26: Management of Nasopharyngeal Carcinoma Wai Tong Ng Roger K.C. Ngan Siu Hong Chan Henry Sze Jimmy Y.W. Chan Anne W.M. Lee
Ch. 27: Multidisciplinary management of oropharynx carcinomas Beth M. Beadle David I. Rosenthal
Ch. 28: Multidisciplinary Management of Hypopharyngeal Carcinoma Marc Hamoir Jean-Pascal Machiels Sandra Schmitz Vincent Gregoire
Ch. 29: Cancers of the Larynx: Tis, T1, T2 Evaluation and Management Carol M. Lewis Steven B. Chinn Chris Holsinger Randal S. Weber
Ch. 30: Diagnosis and Multidisciplinary Treatment of Laryngeal Cancers Nabil F. Saba J. Trad Wadsworth Jonathan J. Beitler Fadlo R. Khuri
Ch. 31: Programs of Organ and Function Preservation Jean Louis Lefebvre
Ch. 32: Principles and New Approaches in Surgical Reconstruction Andreas Dietz Milos Fischer Christina Magill Bruce H. Haughey
Ch. 33: Multidisciplinary treatment of the neck Remco de Bree Johannes A. Langendijk C.R. Leemans
Ch. 34: Postoperative Management of High-Risk Resectable Head and Neck Cancer Assuntina G. Sacco Ezra E. Cohen
Ch. 35: Multidisciplinary Approach of Unresectable Head and Neck Cancer Ricardo Hitt Ana Lopez-Martin Juan J. Cruz Robert I. Haddad
Ch. 36: Management of Salivary Gland Cancer Laura D. Locati Marco Guzzo Ester Orlandi Lisa Licitra
Ch. 37: Primary Mucosal Melanomas of the Head and Neck Juliette Thariat Anne-Catherine Baglin Pierre Yves Marcy Caroline Even Antoine Moya-Plana Yusuke Demizu Adam S. Garden Marco Krengli Michael A. Postow
Ch. 38: Head & Neck Cutaneous Melanoma Mina N. Le Michael A. Postow Snehal G. Patel
Ch. 39: Cervical Lymph Node Metastases Of Squamous Cell Carcinoma From An Unknown Primary Site Nicholas Pavlidis Georgios Plataniotis
Ch. 40: The Management of Thyroid and Parathyroid Cancer Nasheed M. Hossain Colleen Veloski Ranee Mehra
Ch. 41: Head and Neck Paragangliomas Julian Künzel Michael Hainz Heidi Rossmann Christoph Matthias
Ch. 42: Systemic Treatment of Recurrent/Metastatic Squamous Cell Carcinoma of the Head and Neck Petr Szturz Jan B. Vermorken
Ch. 43: Phase I study methodology in head and neck oncology Aaron Hansen Christophe Le Tourneau
Ch. 44: Treatment of the Elderly Head and Neck Cancer Patient Jean-Claude Horiot Matti Aapro
Ch. 45: Normal Tissue Complications and Protection in Head and Neck Cancer Patients Andy Trotti Nikhil Rao Avraham Eisbruch David I. Rosenthal
Ch. 46: Advances in Management of Complications for Head and Neck Cancer Therapy Barbara Murphy Jie Deng Mark J. Stavas Heidi Ganzer Joel B. Epstein
Ch. 47: Rehabilitation of Heavily Treated Head and Neck Cancer Patients Katherine A. Hutcheson
Ch. 48: Salvage Therapy in Head and Neck Cancer Patients John Heaphy Rod Rezaee Pierre Lavertu
Ch. 49: Quality of Life in Head and Neck Cancer Patients Jolie Ringash
Ch. 50: Psycho-oncologic aspects of head and neck cancer patients Michel Reich
Ch. 51: Advances in Nanomedicine for Head and Neck Cancer Sajanlal R. Panikkanvalappil Mostafa A. El-Sayed Ivan H. El-Sayed
Ch. 52: Head and Neck Quality Assurance 2014 Thomas J. FitzGerald Maryann Bishop-Jodoin David S. Followill James M. Galvin Michael V. Knopp Jeff M. Michalski Mark Rosen Jonathan M. Glanzman Paul Rava Allison Sacher David J. Goff Alec Vaezi Kenneth Ulin
Editors: Jacques Bernier
Ch. 1: Epidemiology and Aetiology of Head and Neck Cancers Newell W. Johnson Hemantha K. Amarasinghe
Ch. 2: Head and Neck Cancer Prevention Fausto Chiesa Angelo Ostuni Roberto Grigolato Luca Calabrese Mohssen Ansarin
Ch. 3: Cellular and Molecular Pathology of Head and Neck Tumors Adel K. El-Naggar
Ch. 4: Oncogenomics/Proteomics of Head and Neck Cancers Jason I. Kass Howard S. Moskowitz Jennifer R. Grandis
Ch. 5: Genetics and Epigenetics of Head and Neck Cancer Jagtar Dhanda Richard J. Shaw
Ch. 6: Immunology of Head and Neck Cancer Benjamin A. Kansy Steve C. Lee Robert L. Ferris
Ch. 7: Biomarkers in Head and Neck Cancer Hyunseok Kang Christine H. Chung Arlene A. Forastiere
Ch. 8: HPV and EBV in Head and Neck Cancer Jeffrey Brumbaugh Robert L. Ferris Shen Hu
Ch. 9: Head and Neck Cancer Staging and Prognosis: Perspectives of the UICC and the AJCC Brian O’Sullivan Jatin P. Shah William M. Lydiatt
Ch. 10: Preclinical Models of Head and Neck Squamous Cell Carcinoma C.L. Zuur A.J.C. Dohmen Michiel W. van den Brekel Xiao-Jing Wang Stephen Malkoski
Ch. 11: Translational Research in Head and Neck Oncology David S. Yoo David M. Brizel
Ch. 12: Hypoxia in Head and Neck Cancers: Clinical Relevance and Treatment Yungan Tao Jean Bourhis
Ch. 13: Imaging of Head and Neck Cancers Taha S. Meraj Suyash Mohan Gaurang V. Shah
Ch. 14: Ultrasound Investigations in Head & Neck Cancer Patients Yolanda Y.P. Lee Ka Tak Wong Kunwar Suryaveer Singh Bhatia Anil Tejbhan Ahuja
Ch. 15: Sentinel Node Biopsy Oliver J. Smith Lee W.T. Alkureishi Gary L. Ross
Ch. 16: Intensity-Modulated Radiation Therapy for Head and Neck Cancer Marsha Reyngold Edward J. Shin Nancy Lee
Ch. 17: Stereotactic Radiotherapy in Head and Neck Cancer Patients Thomas Leroy Eric Lartigau
Ch. 18: Proton Beam Therapy for Head and Neck Cancer Danielle N. Margalit Judy A. Adams Hanne M. Kooy Annie W. Chan < Ch. 19: Principles of Systemic Chemotherapy for Squamous Cell Head and Neck Cancer Cristina P. Rodriguez David J. Adelstein
Ch. 20: Molecular Targeted Therapies in Head and Neck Cancer Zachary S. Morris Anne M. Traynor Paul M. Harari
Ch. 21: Laser Endoscopic Treatment Pierre Moreau Pierre Demez
Ch. 22: Transoral robotic surgery in head and neck cancer Sylvain Morinière
Ch. 23: Multidisciplinary Management of Skull Base and Superstructure Tumors Giulio Cantù Carlo L. Solero Stefano Riccio Sarah Colombo Madia Pompilio
Ch. 24: Multidisciplinary management of oral cavity and maxillary sinus cancers Alexander D. Rapidis
Ch. 25: Oral Oncology Ruth Aponte Wesson Theresa M. Hofstede Richard C. Cardoso Pattii Montgomery Alexander M. Won Jack W. Martin Mark S. Chambers
Ch. 26: Management of Nasopharyngeal Carcinoma Wai Tong Ng Roger K.C. Ngan Siu Hong Chan Henry Sze Jimmy Y.W. Chan Anne W.M. Lee
Ch. 27: Multidisciplinary management of oropharynx carcinomas Beth M. Beadle David I. Rosenthal
Ch. 28: Multidisciplinary Management of Hypopharyngeal Carcinoma Marc Hamoir Jean-Pascal Machiels Sandra Schmitz Vincent Gregoire
Ch. 29: Cancers of the Larynx: Tis, T1, T2 Evaluation and Management Carol M. Lewis Steven B. Chinn Chris Holsinger Randal S. Weber
Ch. 30: Diagnosis and Multidisciplinary Treatment of Laryngeal Cancers Nabil F. Saba J. Trad Wadsworth Jonathan J. Beitler Fadlo R. Khuri
Ch. 31: Programs of Organ and Function Preservation Jean Louis Lefebvre
Ch. 32: Principles and New Approaches in Surgical Reconstruction Andreas Dietz Milos Fischer Christina Magill Bruce H. Haughey
Ch. 33: Multidisciplinary treatment of the neck Remco de Bree Johannes A. Langendijk C.R. Leemans
Ch. 34: Postoperative Management of High-Risk Resectable Head and Neck Cancer Assuntina G. Sacco Ezra E. Cohen
Ch. 35: Multidisciplinary Approach of Unresectable Head and Neck Cancer Ricardo Hitt Ana Lopez-Martin Juan J. Cruz Robert I. Haddad
Ch. 36: Management of Salivary Gland Cancer Laura D. Locati Marco Guzzo Ester Orlandi Lisa Licitra
Ch. 37: Primary Mucosal Melanomas of the Head and Neck Juliette Thariat Anne-Catherine Baglin Pierre Yves Marcy Caroline Even Antoine Moya-Plana Yusuke Demizu Adam S. Garden Marco Krengli Michael A. Postow
Ch. 38: Head & Neck Cutaneous Melanoma Mina N. Le Michael A. Postow Snehal G. Patel
Ch. 39: Cervical Lymph Node Metastases Of Squamous Cell Carcinoma From An Unknown Primary Site Nicholas Pavlidis Georgios Plataniotis
Ch. 40: The Management of Thyroid and Parathyroid Cancer Nasheed M. Hossain Colleen Veloski Ranee Mehra
Ch. 41: Head and Neck Paragangliomas Julian Künzel Michael Hainz Heidi Rossmann Christoph Matthias
Ch. 42: Systemic Treatment of Recurrent/Metastatic Squamous Cell Carcinoma of the Head and Neck Petr Szturz Jan B. Vermorken
Ch. 43: Phase I study methodology in head and neck oncology Aaron Hansen Christophe Le Tourneau
Ch. 44: Treatment of the Elderly Head and Neck Cancer Patient Jean-Claude Horiot Matti Aapro
Ch. 45: Normal Tissue Complications and Protection in Head and Neck Cancer Patients Andy Trotti Nikhil Rao Avraham Eisbruch David I. Rosenthal
Ch. 46: Advances in Management of Complications for Head and Neck Cancer Therapy Barbara Murphy Jie Deng Mark J. Stavas Heidi Ganzer Joel B. Epstein
Ch. 47: Rehabilitation of Heavily Treated Head and Neck Cancer Patients Katherine A. Hutcheson
Ch. 48: Salvage Therapy in Head and Neck Cancer Patients John Heaphy Rod Rezaee Pierre Lavertu
Ch. 49: Quality of Life in Head and Neck Cancer Patients Jolie Ringash
Ch. 50: Psycho-oncologic aspects of head and neck cancer patients Michel Reich
Ch. 51: Advances in Nanomedicine for Head and Neck Cancer Sajanlal R. Panikkanvalappil Mostafa A. El-Sayed Ivan H. El-Sayed
Ch. 52: Head and Neck Quality Assurance 2014 Thomas J. FitzGerald Maryann Bishop-Jodoin David S. Followill James M. Galvin Michael V. Knopp Jeff M. Michalski Mark Rosen Jonathan M. Glanzman Paul Rava Allison Sacher David J. Goff Alec Vaezi Kenneth Ulin
"This exceptional, up-to-date resource on the basic and clinical science of head and neck cancer synthesizes a vast amount of information in a single, comprehensive resource. ... Specialists ... as well as trainees in these fields, will find this an outstanding resource. ... an extraordinary guide to this field. Those looking for a comprehensive resource on head and neck cancer will not find a better one. ... it will soon become the definitive book on head and neck cancer." (John David Cramer, Doody's Book Reviews, January, 2017)