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This book identifies relevant approaches of designing effective health communication programs in Africa. The book builds on current knowledge in health communication to suggest strategies of making this universal knowledge applicable in Africa. the author identified relevant theories, African cultural practices,media advocacy, new media, socio-legal perspective and behaviour change communication as the best strategies for health communication in Africa. The book attempts to fill the gap in knowledge in health communication created by the fact that majority of theories and principles were developed in Western countries and their duplication in developing countries has led to inconsistent results. This work is important because it is tailored for use in Sub-Saharan Africa a region with a high burden of disease. The book is meant to play an important role in health communication aimed at HIV and AIDs prevention.