Heart Rate and Rhythm
Gebundenes Buch

Heart Rate and Rhythm

Molecular Basis, Pharmacological Modulation and Clinical Implications

Herausgegeben: Tripathi, Onkar N.; Ravens, Ursula; Sanguinetti, Michael C.
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Pathological heart rhythms are a major health issue. In this book experts from various fields provide an important context for understanding the complicated molecular and cellular mechanisms that underlie normal and pathophysiological cardiac rhythms.Individual chapters cover a full range of topics, including the ionic basis of pacemaking, the role of specific channels and transporters in sinoatrial node pacemaking, altered intracellular Ca2+ handling in response to disease, computer modeling of the action potentials of pacemaker and working cardiomyocytes, genetic and molecular basis of inher...