Jennifer G Treleaven, A John Barrett

Hematopoietic Stem Cell Transplantation in Clinical Practice

• Gebundenes Buch

Produktbeschreibung

A guide to the practice of stem cell transplantation, its status in the treatment of various disorders and the problems that arise after transplantation, aimed at the whole transplant team. * An up to date guide to best practice in the use of stem cell transplantation, covering current status in the treatment of malignant and non-malignant conditions, practical aspects and problems such as infection and graft versus host disease. * Has a practical, accessible approach with free use of algorithms, list tables. * Aimed at the whole transplant team - this is an interdisciplinary field. * International contributor team with editors in the UK and USA. * Illustrated in colour throughout.

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Produktdetails

• Verlag: Elsevier Health Sciences
• Seitenzahl: 568
• Erscheinungstermin: 1. November 2008
• Englisch
• Abmessung: 277mm x 226mm x 33mm
• Gewicht: 1950g
• ISBN-13: 9780443101472
• ISBN-10: 0443101477
• Artikelnr.: 24925068

Inhaltsangabe

PART 1. SETTING THE SCENE Introduction. Essential biology of stem cell
transplantation
PART 2. THE ROLE OF STEM CELL TRANSPLANTATION IN TREATMENT Acute myeloid
leukaemia. Chronic myeloid leukaemia. Acute lymphoblastic leukemia in
adults. Childhood leukemias. The myelodysplastic syndromes. Multiple
myeloma. Hodgkin's disease and non-Hodgkin's lymphoma. Chronic lymphocytic
leukaemia. Solid tumors in children. Breast cancer. Solid tumors in adults.
Germ cell tumors. Primary immunodeficiency diseases. Acquired aplastic
anemia and Fanconi anemia. Thalassaemia and sickle cell disease. Lysosomal
storage disorders. Autoimmune disorders
PART 3. PREPARATION FOR TRANSPLANT Patient selection: preliminary
interview, screening of apient and donor. Stem cell donor registries. Cord
blood banks and umbilical cord blood transplantation in children and
adults. Human leukocyte antigen matching, compatibility testing and donor
selection. Collection and processing of marrow and blood hematopoietic stem
cells. Vascular access. High-dose regimens for autologous stem cell
transplantation. Myeloablative conditioning regimens for allogeneic
transplantation. Reduced-intensity conditioning for allogeneic
hematopoietic stem cell transplantation. Transplants from unrelated or
mismatched family donors. Management of the older patient.
PART 4. POST-TRANSPLANT CARE Transfusion medicine support for hematopoietic
stem cell transplantation. The transplant pharmacopoeia. Nutrition support.
Barrier precautions, prophylaxis and neutropenic fever. Re-immunization
after hematopoietic stem cell transplantation. Psychological and supportive
care issues in the transplant setting.
PART 5. MANAGEMENT OF POST-TRANSPLANT COMPLICATIONS Graft failure. Acute
graft-versus-host disease. Chronic graft-versus-host disease. Management of
relapse and minimal residual disease after stem cell allografting.
Bacterial infections. Viral infections. Fungal infections. Parasitic
infections. Multiple organ failure and intensive care. Late effects.
PART 6. THE WIDER PERSPECTIVE Starting a hemopoietic stem cell transplant
unit. Ethical and legal considerations in stem cell transplantation. How to
build and use a stem cell transplant database. Blood and marrow transplant
organizations. Stem cell transplantation - future prospects.