Nader G. Abraham (Hrsg.)

Heme Oxygenase in Biology and Medicine

Herausgeber: Abraham, Nader G.

• Gebundenes Buch

Produktbeschreibung

The recent convergence of research in stem cell biology, leukemic cell genetics, and drug discovery has provided remarkable insight into pathogenesis and treatment of leukemia and lymphoma. These insights have led to the new therapeutic approaches involving the manipulation of molecular and/or biochemical pathways in leukemia cells. Nonetheless, effective treatment and cures for these blood-related diseases remains, in many cases elusive. This symposium is designed to integrate recent knowledge regarding the basic cellular and molecular biology of leukemia and lymphoma with new approaches to diagnosis and therapy. To this end, a translation research (laboratory to bedside) approach will be encouraged throughout the meeting, with discussions covering new mechanisms regulating hematopoietic cell development, recent new data from clinical trails of new molecular therapeutics, and newly emerging directions in diagnosis. The symposium will bring together basic, translational, and clinical investigators in a meeting aimed at developing potential collaborative interaction. The intension is to provide new insights into the molecular targets for the treatment of blood-related cancers

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Produktdetails

• Verlag: Springer Netherlands
• 2002
• Seitenzahl: 540
• Erscheinungstermin: 31. August 2002
• Englisch
• Abmessung: 260mm x 183mm x 38mm
• Gewicht: 1319g
• ISBN-13: 9780306472640
• ISBN-10: 0306472643
• Artikelnr.: 21020505

Inhaltsangabe

An Overview of Heme Oxygenase; N.G. Abraham. Section I: Physiology/Pathology of Heme Oxygenase and its Products, Carbon Monoxide and Bilirubin. I. Development of Heme Oxygenase Inhibitors for the Prevention of Severe Jaundice in Infants: Studies from Laboratory Bench to New Nursery; A. Kappas. 2. Carbon Monoxide: A Potential Anti-inflammatory Agent and Mediator of Lung Anti-Oxidant Defenses; S.W. Ryter, et al. 3. Correlation of the Altered Vascular Effects of Carbon Monoxide and the Cardiovascular Complications of Diabetes; Rui Wang, et al. 4. Endogenous Carbon Monoxide Has Protective Roles in Neointimal Development Elicited by Arterial Injury; T. Morita, et al. 5. End Tidal Breath Carbon Monoxide (ETCO) Levels in Pregnant Women; D.S. Seidman, et al. 6. The Role of Heme Oxygenase in Pregnancy; P. Hewett, A. Ahmed. 7. Increased Carbon Monoxide in Exhaled Air in Patients with Inflammatory Respiratory Diseases; M. Yamaya, et al. 8. Carbon Monoxide and Iron, by-Products of Heme Oxygenase, Modulate Vascular Endothelial Growth Factor Synthesis in Vascular Smooth Muscle Cells; J. Dulak, et al. Section II: Physiological Function of Heme Oxygenase and the Central Nervous System. 9. CO and Neonatal Cerebral Circulation; C.W. Leffler, et al. 10. Differential Expression of Heme Oxygenase-1 in Rat Brain by Endotoxin (LPS); G. Scapagnini, et al. 11. Role of Heme Catabolism in Neurodegenerative Diseases; A. Takeda, et al. 12. Heme Oxygenase-1 and Alzheimer Disease; Y. Mawal, et al. 13. Early Molecular Mechanisms for the Induction of Neuronal Membran