Hepatitis Delta Virus

Herausgegeben:Casey, John L.

• Broschiertes Buch

Produktbeschreibung

Hepatitis delta virus which causes severe acute and chronic liver disease was discovered following the detection of a novel antigen-antibody system in hepatitis B virus carriers. Currently, HDV is classified as a subviral satellite of hepatitis B virus. However, unlike other satellite viruses, the dependence of HDV on HBV is limited solely to the provision of an envelope of hepatitis B surface antigen for virus assembly. Research into the molecular virology of the HDV life cycle has revealed a fascinating collection of biology. These insights are now beginning to be translated into new potential treatment strategies. There are currently still an estimated 15 million HDV carriers worldwide.

Produktdetails

• Current Topics in Microbiology and Immunology 307
• Verlag: Springer / Springer Berlin Heidelberg / Springer, Berlin
• Artikelnr. des Verlages: 978-3-642-06751-8
• Softcover reprint of hardcover 1st ed. 2006
• Seitenzahl: 244
• Erscheinungstermin: 12. Februar 2010
• Englisch
• Abmessung: 235mm x 155mm x 14mm
• Gewicht: 369g
• ISBN-13: 9783642067518
• ISBN-10: 3642067514
• Artikelnr.: 32073204

Inhaltsangabe

Structure and Replication of Hepatitis Delta Virus RNA.- HDV RNA Replication: Ancient Relic or Primer?.- HDV Ribozymes.- RNA Editing in Hepatitis Delta Virus.- Post-translational Modification of Delta Antigen of Hepatitis D Virus.- The Role of the HBV Envelope Proteins in the HDV Replication Cycle.- Prenylation of HDAg and Antiviral Drug Development.- Hepatitis Delta Virus Genetic Variability: From Genotypes I, II, III to Eight Major Clades?.- Functional and Clinical Significance of Hepatitis D Virus Genotype II Infection.- Immunology of HDV Infection.- The Woodchuck Model of HDV Infection.