Alcoholic liver disease (ALD) develops in patients consuming excessive amounts of alcohol. Alcohol dependency is not always a prerequirement for ALD development. In fact, some patients develop ALD and, in particular, cirrhosis without a history of dependence. Moreover, the severity of disease does not always correlate with the amount of alcohol intake, and environmental and genetic factors likely play a crucial role in ALD development. Although a dose-effect relationship between alcohol intake and alcohol-induced hepatic damage has been reported, no set amount of alcohol consumption that could surely predict the development of ALD.
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