Use of chemical substances as an aid for the disinfection and removal of infected tissue from the root canal space has been a constitutive part of the objective of endodontic treatment since time immemorial. Over the past decade, there has been a paradigm shift towards the utilization of phytochemicals in the field of Endodontics which has been prodigious. India is well known for its rich heritage of traditional medicinal systems. The associated cytotoxic effects with currently used synthetic agents has inflated the interest in drugs derived from remedial plants. Literature has proven the benefits of phytotherapy in Dentistry, including their role as Endodontic irrigants. This book delineates the diverse Herbal Endodontic irrigants and highlights their potential use in near future.