John L. Markley / Dexter B. Northrop / Catherine A. Royer (eds.)

High-Pressure Effects in Molecular Biophysics and Enzymology

Herausgeber: Markley, John L; Royer, Catherine A; Northrop, Dexter B

• Gebundenes Buch

Produktbeschreibung

Written by the best researchers in the field, this timely book explores the use of high pressure in connection with spectroscopy as a research tool in biophysics and biochemistry. It covers subjects such as pressure tunning spectroscopy for investigating molecular interactions; high-pressure FT-IR studies of the secondary structure of proteins; structural, functional, and kinetic aspects of nucleic acid-protein complexes with pressure; sequence, salt, charge, and the stability of DNA at high pressure; steady-state enzyme kinetics at high pressure; membrane-free volume with bulky lipid concentration by regular distribution; and pressure and temperature induced inactivation of microorganisms.

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This book presents an overview of current research on pressure perturbations on enzyme kinetics, protein folding and structure, lipid bilayer structure and organization, lipid-protein interactions, DNA structure, and protein-ligand interactions.

Produktdetails

• Verlag: Oxford University Press, USA
• Seitenzahl: 400
• Erscheinungstermin: 12. September 1996
• Englisch
• Abmessung: 242mm x 163mm x 28mm
• Gewicht: 708g
• ISBN-13: 9780195097221
• ISBN-10: 019509722X
• Artikelnr.: 21078897

Inhaltsangabe

* 1: Resolution of the Ambiguity of Vam't Hoff Plots by the Effect of
Pressure Upon the Equilibrium
* 2: Pressure Tunning Spectroscopy - A Tool for Investigating Molecular
Interactions
* 3: Use of Partial Molar Volumes of Model Compounds in the
Interpretation of High-Pressure Effects on Proteins
* 4: Pressure-tunning Spectroscopy of Proteins: Fourier Transform
Infrared Studies in the Diamond Anvil Cell
* 5: Temperature and Pressure-Induced Unfolding of a Mutant of
Staphylococcal Nuclease A
* 6: Pressure-Jump Relaxation Kinetics of Unfolding and Refolding
Transitions of Staphylococcal Nuclease and Proline Isomerization
Mutants
* 7: High-Pressure FT-IR Studies of the Secondary Structure of Proteins
* 8: High-Pressure NMR Studies of the Dissociation of Arc Repressor and
the Cold Denaturation of Ribonuclease A
* 9: Exploring Structural, Functional, and Kinetic Aspects of Nucleic
Acid-Protein Complexes with Pressure: Nucleosomes and RNA Polymerase
* 10: Pressure and Cold Denaturation of Proteins, Protein-DNA
Complexes, and Viruses
* 11: Sequence, Salt, Charge, and the Stability of DNA at High Pressure
* 12: The Application of Pressure Relaxation to the Study of Substrate
Binding to Cytochrome P versus Temperature, Pressure, and Viscosity
* 13: Pressure Effects on the Ligand Binding Kinetics for Hemoproteins
and Their Site-Directed Mutants
* 14: Steady-State Enzyme Kinetics at High Pressure
* 15: Transient Enzyme Kinetics at High Pressure
* 16: The Effects of High Pressure on the Allosteric Properties of
Phosphofructokinase from Escherichia coli
* 17: Correlation Field Splitting of Chain Vibrations: Structure and
Dynamics in Lipid Bilayers and Biomembranes
* 18: High Pressure Effects on the Structure and Phase Behavior of
Model Membranes Systems
* 19: Membrane-Free Volume with Bulky Lipid Concentration by Regular
Distribution: A Functionally Important Membrane Property Explored by
Pressure Studies of Pyrene-Labelled Phosphatidylcholine
* 20: NMR Studies of the Order and Dynamics of
Dipalmitoylphosphatidylcholine Bilayers as a Function of Pressure
* 21: The Effects of Increased Viscosity on the Function of Integral
Membrane Proteins
* 22: Pressure and Temperature Induced Inactivation of Microorganisms
* 23: Osmotic and Hydrostatic Pressure as Tools to Study Molecular
Recognition