The current study was undertaken to investigate time-dependent toxic effect of sub-lethal dose of orally administered Aluminium Chloride in male rabbits (oryctolagus cuniculus) on the histology of renal tisues. Animals were divided into control and treated groups. Animals of treated group received Aluminium Chloride at the dose rate of 25 mg/kg disolved in 0.9% saline solution after every 48 hours, for 15 and 30 days respectively while animals of control group were given 0.9% saline solution only. Animals were dissected with the interval of 15 days. Renal tissues were processed and stained by Hematoxylin and Eosin for Histological studies. Histological changes induced in the renal tissues of treated animals were observed. The basic purpose of this research was to administer the toxicity of Aluminium Cholride in Kidney of rabbits.