This monograph covers issues related to the history of foreign diplomatic relations of Central Asian khanates in the 18th and 19th centuries. In particular, in the 16th-19th centuries, Central Asia, which was one of the hotbeds of social-economic, political life, and world civilization in the 16th-19th centuries, began to be cut off from world trade as a result of the decline of the importance of the Great Silk Road. This situation, in turn, hurt the socio-economic development of the khanates. Regardless of the political situation prevailing in the domestic life of the countries of Estonia, Iran, and China, the information about the trade and economic relations of the Central Asian khanates with the neighbouring countries is highlighted.