HIV Antiretroviral Drug Resistance in North India - Azam, Mohd
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A major cause of failure of antiretroviral therapy (ART) is the presence of drug-resistance-associated mutations in the polymerase gene of HIV-1. The paucity of data regarding potential drug resistance to protease inhibitors (PIs) and reverse transcriptase inhibitors (RTIs) prompted us to carry out this study. This information not only will shed light on the extent of current drug resistance in HIV strains but also will aid in patient treatment and drug designing. Our observations through this study illustrated that there is an urgent need to tailor ART drug regimens to the individual to achieve optimum therapeutic outcome in North India.…mehr

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Produktbeschreibung
A major cause of failure of antiretroviral therapy (ART) is the presence of drug-resistance-associated mutations in the polymerase gene of HIV-1. The paucity of data regarding potential drug resistance to protease inhibitors (PIs) and reverse transcriptase inhibitors (RTIs) prompted us to carry out this study. This information not only will shed light on the extent of current drug resistance in HIV strains but also will aid in patient treatment and drug designing. Our observations through this study illustrated that there is an urgent need to tailor ART drug regimens to the individual to achieve optimum therapeutic outcome in North India.
Autorenporträt
Dr. Mohd Azam,Research Scientist.Viral Research and Diagnostic Laboratory, A.M.U., Aligarh.PhD in Medical Microbiology from Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh (India) and National Centre for Disease Control, New Delhi (India).